Homework Help is Here – Start Your Trial Now!
Science
Biology
Suppose you discover a drug that has potential antiviral effect against SARS-CoV2 so you tested its effect on the expression of selected genes that are upregulated during COVID19 infection. IFH1 and ISG15 activates the innate immune response in the presence of viral RNA while IFNy activates both innate and adaptive immune responses. MX1 is a proviral factor that enhances viral replication in the cell. To determine how the drug affect these genes, you performed microarray using treated and untreated cells that were infected with SARS-CoV2. You labelled cDNAs from treated cells with green fluorescence while cDNAs from untreated cells were labelled red. You obtained the following results in the microarray chip for each gene: IF1H1 IFNY ISG15 MX1 Based on the results above, which of the following genes is upregulated by the antiviral drug? a. IF1H1 O b. IFNY C. MX1 d. ISG15

Suppose you discover a drug that has potential antiviral effect against SARS-CoV2 so you tested its effect on the expression of selected genes that are upregulated during COVID19 infection. IFH1 and ISG15 activates the innate immune response in the presence of viral RNA while IFNy activates both innate and adaptive immune responses. MX1 is a proviral factor that enhances viral replication in the cell. To determine how the drug affect these genes, you performed microarray using treated and untreated cells that were infected with SARS-CoV2. You labelled cDNAs from treated cells with green fluorescence while cDNAs from untreated cells were labelled red. You obtained the following results in the microarray chip for each gene: IF1H1 IFNY ISG15 MX1 Based on the results above, which of the following genes is upregulated by the antiviral drug? a. IF1H1 O b. IFNY C. MX1 d. ISG15

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
Question
Suppose you discover a drug that has potential antiviral effect against SARS-CoV2 so you tested its effect on the expression of selected genes that are upregulated during COVID19 infection. IFH1 and ISG15 activates the innate immune response in the presence of viral RNA while IFNy activates both innate and adaptive immune responses. MX1 is a proviral factor that enhances viral replication in the cell. To determine how the drug affect these genes, you performed microarray using treated and untreated cells that were infected with SARS-CoV2. You labelled cDNAs from treated cells with green fluorescence while cDNAs from untreated cells were labelled red. You obtained the following results in the microarray chip for each gene: IF1H1 IFNY ISG15 MX1 Based on the results above, which of the following genes is upregulated by the antiviral drug? a. IF1H1 O b. IFNY C. MX1 d. ISG15
Transcribed Image Text:Suppose you discover a drug that has potential antiviral effect against SARS-CoV2 so you tested its effect on the expression of selected genes that are upregulated during COVID19 infection. IFH1 and ISG15 activates the innate immune response in the presence of viral RNA while IFNy activates both innate and adaptive immune responses. MX1 is a proviral factor that enhances viral replication in the cell. To determine how the drug affect these genes, you performed microarray using treated and untreated cells that were infected with SARS-CoV2. You labelled cDNAs from treated cells with green fluorescence while cDNAs from untreated cells were labelled red. You obtained the following results in the microarray chip for each gene: IF1H1 IFNY ISG15 MX1 Based on the results above, which of the following genes is upregulated by the antiviral drug? a. IF1H1 O b. IFNY C. MX1 d. ISG15
Suppose you discover a drug that has potential antiviral effect against SARS-CoV2 so you tested its effect on the expression of selected genes that are upregulated during COVID19 infection. IFH1 and ISG15 activates the innate immune response in the presence of viral RNA while IFNy activates both innate and adaptive immune responses. MX1 is a proviral factor that enhances viral replication in the cell. To determine how the drug affect these genes, you performed microarray using treated and untreated cells that were infected with SARS-CoV2. You labelled cDNAs from treated cells with green fluorescence while cDNAs from untreated cells were labelled red. You obtained the following results in the microarray chip for each gene: IF1H1 IFNY ISG15 MX1 Based on the results above, which of the following genes is downregulated by the antiviral drug? a. IF1H1 ISG15 MX1 IFNy O b. O c. O d.
Transcribed Image Text:Suppose you discover a drug that has potential antiviral effect against SARS-CoV2 so you tested its effect on the expression of selected genes that are upregulated during COVID19 infection. IFH1 and ISG15 activates the innate immune response in the presence of viral RNA while IFNy activates both innate and adaptive immune responses. MX1 is a proviral factor that enhances viral replication in the cell. To determine how the drug affect these genes, you performed microarray using treated and untreated cells that were infected with SARS-CoV2. You labelled cDNAs from treated cells with green fluorescence while cDNAs from untreated cells were labelled red. You obtained the following results in the microarray chip for each gene: IF1H1 IFNY ISG15 MX1 Based on the results above, which of the following genes is downregulated by the antiviral drug? a. IF1H1 ISG15 MX1 IFNy O b. O c. O d.
Expert Solution
steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Immunoglobulins
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education
SEE MORE TEXTBOOKS