Suppose you had a bacteriophage λ in which the gene encoding the cro protein had been mutated, so that it had an unusually high affinity for pL - in this phage the first promoter repressed by cro would be pL, not pRM. What effect, if any, would this mutation, and the consequent rapid repression of transcription from pL, have on the outcome of a cell being infected by this mutant bacteriophage? Explain why you would predict that outcome of an infection by this mutant phage.

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
Chapter5: Abbreviations And Systems Of Measurement
Section: Chapter Questions
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Suppose you had a bacteriophage λ in which the gene encoding the cro protein had been mutated, so that it had an unusually high affinity for pL - in this phage the first promoter repressed by cro would be pL, not pRM. What effect, if any, would this mutation, and the consequent rapid repression of transcription from pL, have on the outcome of a cell being infected by this mutant bacteriophage? Explain why you would predict that outcome of an
infection by this mutant phage. 

lysogeny
lytic
genes
N
cl
cro
cll
genes
tL1
pl t
pRE
pR
tR1
tR2 pR'
tR3
pRM
Transcribed Image Text:lysogeny lytic genes N cl cro cll genes tL1 pl t pRE pR tR1 tR2 pR' tR3 pRM
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