SV40 vectors are derived from Which of the following term is appropriate for the blank? Lütfen birini seçin: O a. Plant cell O b. Simian virus 40 O c. Herpes virus O d. Bacteria O e. Corona virus
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- Using retroviral vectors for gene therapy might increase the patient's risk of developing cancer because they might: a. introduce proteins from the virusb. integrate recombinant DNA into the genome in ways that misregulate the expression of genes at or near the site of integrationc. not express the genes that were introduced into a patient's cellsd. not integrate their recombinant DNA into the patient's genomeAll of the following statements about polioviruses are correct except _____. a. Poliovirus vaccines are produced in both inactivated and live-attenuated forms. b. The oral poliovirus vaccine is composed of three liveattenuated viral strains. c. Poliovirus infects both humans and cattle. d. If genetic reversion of strain 3 occurs when the virus is replicating in vaccinated people, pathogenesis may occur. e. In the United States, the recommended vaccine for poliovirus is the inactivated poliovirus vaccine (IPV).A virophage is best descirbed as:(a) A bacteriophage that requires a helper virus(b) An animal virus that can also infect bacteria(c) A giant virus(d) A phage that is used therapeutically to treat bacterialinfections(e) A satellite virus that inhabits its helper virus (i.e., itshost virus)
- Discuss the advantages and disadvantages of the use of the following viruses as vectors a. Retroviruses b. Adenoviruses c. Adeno-associated virusesThe major issue associated with the use of live, attenuated virus for vaccines is _____. A) reversion to virulent strain that causes disease B) ineffectiveness because it’s not “the real thing” C) contamination with other viruses or bacteria D) the capacity to induce shock in recipientsVirology: Describe two differences for making genomic and messager RNAs between Polio Virus and vesicular Stomatitis Virus .
- Coronaviruses have a positive-sense single stranded RNA genome. a.) What is the genome replication strategy of this category of viruses? b.) How do you think this feature affects the stability of the viral genome? (hint use figure below) Mutation rates in different types of viruses. Estimates obtained for viruses belonging to the major indicated groups are shown as a function of genome size. This reveals an effect of genetic material (RNA/DNA) and genome size on viral mutation rates.The Sabin vaccine contains ______. A) a mixture of bacteria and live, attenuated poliovirus B) a piece of the poliovirus C) inactivated poliovirus D) live, unattended poliovirusYou have been hired by a major pharmaceutical company to develop a new vaccine toprevent COVID-19 infection and spread.a. What is a virus? Describe the viral life cycle. (3 marks)b. Describe the difference between an antiviral drug and a vaccine. (1 mark)c. What are three qualities you would prioritize when developing this new vaccine forCOVID-19 that you would want in the end-product? (6 marks) Note: Qualities should be overarching characteristics of the developed drug, not specifics regarding various molecular mechanisms of action
- Following the infection of healthy tobacco leaves by reconstitutedviruses, what two characteristics did Fraenkel-Conrat andSinger analyze? Explain how their results were consistent withthe idea that the RNA of TMV is responsible for the traits ofthe virus.Transmission studies suggest that there are at least three (3) different variants of the SARS-CoV-2 virus circulating in Latin America and the Caribbean. Discuss a recombinant DNA technology strategy that could be used to verify this claim.The major difference between retrotransposons and retroviruses isa. retrotransposons encode reverse transcriptase.b. retroviruses move from one site in the genome toanother.c. retroviruses encode the env gene, which allows themto move from one cell to another.d. None of the above are correct.