Table 2. Relative risks (RRS) and 95% confidence intervals (CIS) for second cancers after invasive breast cancer associated with body mass index (per 5 kg/m²), Kaiser Permanente Breast Cancer Survivors Cohort (1990-2017) Outcome All cancers Obesity-related cancers Breast cancers ER-positive breast cancers No. of cancers 822 508 333 231 Person-years 47 691 47 691 47 691 47 691 Unadjusted RR (95% CI) 1.05 (1.00 to 1.11) 1.09 (1.02 to 1.17) 1.09 (1.00 to 1.19) 1.12 (1.01 to 1.24) pb .06 .01 .046 .03 Adjusted" RR (95% CI) 1.07 (1.01 to 1.14) 1.13 (1.05 to 1.21) 1.11 (1.02 to 1.21) 1.15 (1.04 to 1.27) pb .01 <.001 .01 008 "Adjusted for study site, race and ethnicity, age, comorbidity index, receipt of radiation, receipt of chemotherapy, receipt of hormonal therapy, ER and PR status, stage, and year of initial breast cancer diagnosis. P values reflect 2-sided x² tests.

Table 2. Relative risks (RRS) and 95% confidence intervals (CIS) for second cancers after invasive breast cancer associated with body mass index (per 5 kg/m²), Kaiser Permanente Breast Cancer Survivors Cohort (1990-2017) Outcome All cancers Obesity-related cancers Breast cancers ER-positive breast cancers No. of cancers 822 508 333 231 Person-years 47 691 47 691 47 691 47 691 Unadjusted RR (95% CI) 1.05 (1.00 to 1.11) 1.09 (1.02 to 1.17) 1.09 (1.00 to 1.19) 1.12 (1.01 to 1.24) pb .06 .01 .046 .03 Adjusted" RR (95% CI) 1.07 (1.01 to 1.14) 1.13 (1.05 to 1.21) 1.11 (1.02 to 1.21) 1.15 (1.04 to 1.27) pb .01 <.001 .01 008 "Adjusted for study site, race and ethnicity, age, comorbidity index, receipt of radiation, receipt of chemotherapy, receipt of hormonal therapy, ER and PR status, stage, and year of initial breast cancer diagnosis. P values reflect 2-sided x² tests.

Calculus For The Life Sciences

2nd Edition

ISBN:9780321964038

Author:GREENWELL, Raymond N., RITCHEY, Nathan P., Lial, Margaret L.

Publisher:GREENWELL, Raymond N., RITCHEY, Nathan P., Lial, Margaret L.

Chapter13: Probability And Calculus

Section13.2: Expected Value And Variance Of Continuous Random Variables

Problem 10E

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