The Claisen condensation converts two molecules of an ester into a B-keto ester. The reaction starts with the ester in an alkoxide/alcohol solution and is worked up with acid to form the neutral B-keto ester product. in 1. "OCH,CH3 / CH;CH2OH 2 2. H30* Show the curved-arrow mechanism for the Claisen condensation of ethyl ethanoate treated with ethoxide ion. Include all formal charges and nonbonding electrons. In each step, draw only the species that react in that step. If an enolate resonance form is possible, draw only the carbanionic form. If a CH, group is being deprotonated, draw all H's on the reacting site. Tip: always omit ethanol byproducts. tep 4c: Draw the resulting structure or structures indicated by the curved-arrow mechanism shown. Include formal charges, ut not lone pairs. :0: :0: H H 1

The Claisen condensation converts two molecules of an ester into a B-keto ester. The reaction starts with the ester in an alkoxide/alcohol solution and is worked up with acid to form the neutral B-keto ester product. in 1. "OCH,CH3 / CH;CH2OH 2 2. H30* Show the curved-arrow mechanism for the Claisen condensation of ethyl ethanoate treated with ethoxide ion. Include all formal charges and nonbonding electrons. In each step, draw only the species that react in that step. If an enolate resonance form is possible, draw only the carbanionic form. If a CH, group is being deprotonated, draw all H's on the reacting site. Tip: always omit ethanol byproducts. tep 4c: Draw the resulting structure or structures indicated by the curved-arrow mechanism shown. Include formal charges, ut not lone pairs. :0: :0: H H 1

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter16: Aldehydes And Ketones

Section: Chapter Questions

Problem 16.26P: Wittig reactions with the following -chloroethers can be used for the synthesis of aldehydes and...

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