suppose the cytosolic pH of Plasmodium is 7.1. Suppose PfCRT is a secondary active symporter using protons to drive VF-6-2 efflux from the digestive vacuole, DV. Suppose the membrane potential across the DV membrane is 50mV, inside positive. VF-6-2 has a 3nM concentration inside the DV and a 56nM concentration in the cytosol. What pH must the P-type ATPase establish inside of a digestive vacuole in order to allow PfCRT to spontaneously transport 1 VF-6-2 out of the DV with 1 H+ at 37°C??
suppose the cytosolic pH of Plasmodium is 7.1. Suppose PfCRT is a secondary active symporter using protons to drive VF-6-2 efflux from the digestive vacuole, DV. Suppose the membrane potential across the DV membrane is 50mV, inside positive. VF-6-2 has a 3nM concentration inside the DV and a 56nM concentration in the cytosol. What pH must the P-type ATPase establish inside of a digestive vacuole in order to allow PfCRT to spontaneously transport 1 VF-6-2 out of the DV with 1 H+ at 37°C??
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter18: Glycolysis
Section: Chapter Questions
Problem 13P
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suppose the cytosolic pH of Plasmodium is 7.1. Suppose PfCRT is a secondary active symporter using protons to drive VF-6-2 efflux from the digestive vacuole, DV. Suppose the membrane potential across the DV membrane is 50mV, inside positive. VF-6-2 has a 3nM concentration inside the DV and a 56nM concentration in the cytosol. What pH must the P-type ATPase establish inside of a digestive vacuole in order to allow PfCRT to spontaneously transport 1 VF-6-2 out of the DV with 1 H+ at 37°C??
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