Focusing on the mechanism linking complex I and ATP synthase depicted in figure 3 in the article, compare that hypothetical mechanism to the classical presentation described in textbooks. What are the major differences between this mechanism and Peter Mitchel’s original chemiosmotic theory? What are the similarities. matrix side or n sideNADH + H+ NAD+complex IU: UDESODOputative proton current byBrownian motionADP + Pia subunitOGF1 ATP synthaseOHОН ОН ОН ОНdo < odHOFO ATP synthaseHOОН ОН ОН ОН ОНputative proton tunnellingthrough a subunitOHATP00glutamic 58of c subunitperiplsmatic side or p sideFigure 3. A possible H+ circuit inside respiring membrane. The phosphate groups of phospholipids on both sides of the membrane are shown by brown ellipsoids.The image proposes that the H+ (red dotted line) are transferred to the Glu 58 (E58) at the centre of subunit c through subunit a of ATP synthase by protontunnelling. H+ would flow from the periplasmic side, always bound to phospholipid heads. This can be arranged in each layer of the membrane.

ETC is an arrangement of protein complexes and some non-protein components in an increasing redox…

Focusing on the mechanism linking complex I and ATP synthase depicted in figure 3 in the article, compare that hypothetical mechanism to the classical presentation described in textbooks. What are the major differences between this mechanism and Peter Mitchel’s original chemiosmotic theory? What are the similarities.

Focusing on the mechanism linking complex I and ATP synthase depicted in figure 3 in the article, compare that hypothetical mechanism to the classical presentation described in textbooks. What are the major differences between this mechanism and Peter Mitchel’s original chemiosmotic theory? What are the similarities.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter27: Metabolic Integration And Organ Specialization

Section: Chapter Questions

Problem 3P

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