The diagram shown represents the coding strand of the myosin gene. Mutations in myosin can lead to muscle defects during development. Using what you know about how mutations can affect transcriptional and post-transcriptional regulation, match the results shown on the Northern (mature mRNA) to the mutations shown. The N lane shows the size and amount expected for non-mutated myosin mRNA. All samples were loaded at the top (-) side of the gel. Part 1. Which lane or lanes on the gel could be the result of mutation A? 00000 I lane 1 lane 2 lane 3 lane 4 lane 5 TATAA Mutation A. Deletion of indicated 2 nucleotides AUG TSS Mutation B. Deletion of 150 nucleotides N 1 2 3 4 5 UAA Mutation C. 3 nucleotides changed

The diagram shown represents the coding strand of the myosin gene. Mutations in myosin can lead to muscle defects during development. Using what you know about how mutations can affect transcriptional and post-transcriptional regulation, match the results shown on the Northern (mature mRNA) to the mutations shown. The N lane shows the size and amount expected for non-mutated myosin mRNA. All samples were loaded at the top (-) side of the gel. Part 1. Which lane or lanes on the gel could be the result of mutation A? 00000 I lane 1 lane 2 lane 3 lane 4 lane 5 TATAA Mutation A. Deletion of indicated 2 nucleotides AUG TSS Mutation B. Deletion of 150 nucleotides N 1 2 3 4 5 UAA Mutation C. 3 nucleotides changed

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Description: The diagram shown represents the coding strand of the myosin gene. Mutations in myosin can lead to muscle defects during development. Using what you know about how mutations canaffect transcriptional and post-transcriptional regulation, match the re

Concepts of Biology

1st Edition

ISBN:9781938168116

Author:Samantha Fowler, Rebecca Roush, James Wise

Publisher:Samantha Fowler, Rebecca Roush, James Wise

Chapter9: Molecular Biology

Section: Chapter Questions

Problem 10RQ: Control of gene expression in eukaryotic cells occurs at which level(s)? a. only the transcriptional...

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The diagram below shows the structure of DNA from the level of a gene to a condensed mitotic chromosome. At each of the four locations marked, indicate how a gene may be regulated by selecting from the choices given. Some answer choices may fit into more than one position; however, you should use each answer choice only once. Choices given: Alternative splicing within the gene sequence can lead to different forms of mRNA. A promoter region can be blocked by another protein. Histone deacetylation can prevent DNA from unwinding. A regulatory region can be bound and increase transcription rates.
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Given the following schematic for a gene and its associated regulatory regions, answer the following questions by placing the correct letter in the provided blanks please put in the correct letter for the questions What region would provide cell type-specific expression of genes? region What site would significantly increase gene expression rates? = region What region or regions of this gene’s coding sequence are expressed as amino acids = region
For each statement about gene expression mechanisms, choose the correct end to the sentence. For each gene, the template strand for transcription is determined by…. The direction of translation is determined by…… The tissue-specificity of protein production is determined by…. choices: a. location of the start codon b. location of the promoter c. direction of polymerization by RNA polymerase d. none of these e. direction of movement of ribosomes f. overall orientation of the chromosome
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Given the following mRNA, write the double-stranded DNA segment that served as the template. Indicate both the 5 and the 3 ends of both DNA strands. Also write out the tRNA anticodons and the amino acid sequence of the protein encoded by the mRNA message. DNA: mRNA: 5-CCGCAUGUUCAGUGGGCGUAAACACUGA-3 protein: tRNA:
What would happen to an mRNA produced from a gene that contained a mutation in the 3'UTR region that deleted a cis-element required for poly A tailing?Question 20 options: The mRNA would be exported to the cytoplasm but would not be translated very efficiently The mRNA would never be exported to the cytoplasm The mRNA would not be spliced or exported to the cytoplasm The mRNA would be translated into a mutant protein
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