The drug Buckeyium binds to the NMDA receptor at the orthosteric binding site (were glutamate would normally bind). Assume that glycine is already bound, and that magnesium is not blocking the NMDAR ion channel. If the channel does not open as a result of Buckeyium binding than Buckeyium would be considered a ____________. A. Indirect Antagonist B. Positive Allosteric Modulator C. Negative Allosteric Modulator D. None of the choice options are correct E. Non-Competitive Antagonist

The drug Buckeyium binds to the NMDA receptor at the orthosteric binding site (were glutamate would normally bind). Assume that glycine is already bound, and that magnesium is not blocking the NMDAR ion channel. If the channel does not open as a result of Buckeyium binding than Buckeyium would be considered a ____________. A. Indirect Antagonist B. Positive Allosteric Modulator C. Negative Allosteric Modulator D. None of the choice options are correct E. Non-Competitive Antagonist

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter4: Principles Of Neural And Hormonal Communication

Section: Chapter Questions

Problem 14RE: A common membrane-bound intermediary between the receptor and the effector protein within the plasma...

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