Explain whether the specificity of interaction will be high or low for each given situation. a. The value of KD of the ligand's interaction to the target receptor is very much lower than the value of KD of the ligand's interaction to off-targets. b. The ligand concentration [L] is higher than the KD value of its interaction with the target and the KD value of its interaction to off-targets.

Human Physiology: From Cells to Systems (MindTap Course List)
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Chapter4: Principles Of Neural And Hormonal Communication
Section4.5: Intercellular Communication And Signal Transduction
Problem 3CYU: Outline the three general means by which binding of a water soluble extracellular chemical messenger...
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Explain whether the specificity of interaction will be high or low for each given situation.

a. The value of KD of the ligand's interaction to the target receptor is very much lower than the value of KD of the ligand's interaction to off-targets.

b. The ligand concentration [L] is higher than the Kvalue of its interaction with the target and the Kvalue of its interaction to off-targets.

 

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