The expression of antigen A or antigen B in red blood cells requires the help of an H antigen. A recessive mutation (h) that prevents the synthesis of the H antigen also prevents the expression of A and B antigens. This is called the Bombay effect. There is no ill effect in an individual with this mutation, but complications with blood transfusions or parental disputes may arise. b. Eva’s parents, John and Cher. Are both type AB. John questioned Cher’s fidelity when Eva turned out to be a type O. Assuming that Cher is indeed loyal to her husband, why did Eva turn out to be type O? Help Cher prove her innocence by showing the possible genotypes of John and Cher. Show also the COMPLETE cross that produced Eva.

Human Biology (MindTap Course List)
11th Edition
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cecie Starr, Beverly McMillan
Chapter19: Introduction To Genetics
Section: Chapter Questions
Problem 6CT: The ABO blood system has been used to settle cases of disputed paternity. Suppose, as a geneticist,...
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The expression of antigen A or antigen B in red blood cells requires the help of an H antigen. A recessive mutation (h) that prevents the synthesis of the H antigen also prevents the expression of A and B antigens. This is called the Bombay effect. There is no ill effect in an individual with this mutation, but complications with blood transfusions or parental disputes may arise.

b. Eva’s parents, John and Cher. Are both type AB. John questioned Cher’s fidelity when Eva turned
out to be a type O. Assuming that Cher is indeed loyal to her husband, why did Eva turn out to be
type O? Help Cher prove her innocence by showing the possible genotypes of John and Cher. Show also
the COMPLETE cross that produced Eva.

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