The father of three sons and two daughters begins to show symptoms of Huntington disease. What is the probability that Sam, the man’s second oldest son (II-2), will suffer from the disease if he lives a normal life span? Sam’s mother and her ancestors do not have the disease. Sam's father was adopted, so we do not know his biological family history for Huntington disease. Explore all possible outcomes for Sam and explain your reasoning. What about the risk to Sam's sisters? Would that be the same or not?

The father of three sons and two daughters begins to show symptoms of Huntington disease. What is the probability that Sam, the man’s second oldest son (II-2), will suffer from the disease if he lives a normal life span? Sam’s mother and her ancestors do not have the disease. Sam's father was adopted, so we do not know his biological family history for Huntington disease. Explore all possible outcomes for Sam and explain your reasoning. What about the risk to Sam's sisters? Would that be the same or not?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter18: Genetics Of Behavior

Section: Chapter Questions

Problem 14QP: A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known...

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The father of three sons and two daughters begins to show symptoms of Huntington's disease. What is the probability that Sam, the man’s second oldest son (II-2), will suffer from the disease if he lives a normal life span? Sam’s mother and her ancestors do not have the disease. Sam's father was adopted, so we do not know his biological family history for Huntington disease. Explore all possible outcomes for Sam and explain your reasoning. What about the risk to Sam's sisters? Would that be the same or not?
What are newest advances in early diagnosis and confirmation of Huntington disease? Explain the difference in inheritance pattern and the frequency to have affected progeny in the case of these three inherited diseases: Huntington, Cystic fibrosis and Duchenne muscular dystrophy. What therapies can be used or recommended for patients experiencing any of these inherited diseases?
a. A man who does not have Huntington’s Disease has children with a woman with Huntington’s Disease whose mother did not have Huntington’s Disease. What proportion of their children would be expected to have Huntington’s Disease b.A man who does have Huntington’s Disease and a woman who does not have Huntington’s Disease have a child who does not have Huntington’s Disease. What is the man’s genotype c.A man who does have Huntington’s Disease and a woman who does not have Huntington’s Disease have eight children, all of whom have Huntington’s Disease. Can you be certain of the man’s genotype? Why or why not? What genotype is MOST likely and why
Huntington disease is a rare dominant trait that causes neurodegeneration later in life. A man in his thirties, who already has threechildren, discovers that his mother has Huntington disease thoughhis father is unaffected. What are the following probabilities?A. That the man in his thirties will develop Huntington disease.B. That his first child will develop Huntington disease.C. That one out of three of his children will develop Huntingtondisease.
A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known concordance statistics, would his MZ twin be at high risk for the disease? Would the twins risk decrease if he were raised in an environment different from that of his schizophrenic brother?
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How is this disorder inherited? State your reasoning
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