The following questions deal with a fundamental understanding of enzyme catalysis. a. Why is the rate of an enzyme-catalyzed reaction proportional to the amount of (ES) complex? b. What do you think is meant by saturation of the enzyme? c. What do you think is meant by the term “saturation kinetics”? d. How does the Michaelis-Menten equation explain why the rate of an enzyme-catalyzed reaction reaches a maximum value at high [S]?

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