The inhibitory effect for an enzyme-catalyzed reaction is demonstrated by the following mechanism. Derive the equation that gives the reaction rate expression for this mechanism. Ks E+S kcat ES > E +P Ki 8K ESI El +S 8K,

The inhibitory effect for an enzyme-catalyzed reaction is demonstrated by the following mechanism. Derive the equation that gives the reaction rate expression for this mechanism. Ks E+S kcat ES > E +P Ki 8K ESI El +S 8K,

Principles of Modern Chemistry

8th Edition

ISBN:9781305079113

Author:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler

Publisher:David W. Oxtoby, H. Pat Gillis, Laurie J. Butler

Chapter18: Chemical Kinetics

Section: Chapter Questions

Problem 75AP

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Question

The inhibitory effect for an enzyme-catalyzed reaction is demonstrated by the following
mechanism. Derive the equation that gives the reaction rate expression for this mechanism.
kcat
ES E+P
Ks
E+S =
d+3 +
Ki
El +S ESI
8K,

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