The Merck Index indicates that 10 mg of guanidine, CH5N3, may be administered for each kilogram of body mass in the treatment of myasthenia gravis. The nitrogen in a 4-tablet sample that had a total mass of 7.50 g was converted to ammonia by a Kjeldahl digestion, followed by distillation into 100.0 mL of 0.1750 M HCl. The analysis was completed by titrating the excess acid with 11.37 mL of 0.1080 M NaOH. How many of these tablets represent a proper dose for a patient who weighs (a) 100 lb, (b) 150 lb, and (c) 275 lb?

Fundamentals Of Analytical Chemistry
9th Edition
ISBN:9781285640686
Author:Skoog
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Chapter16: Applications Of Neutralization Titrations
Section: Chapter Questions
Problem 16.34QAP
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The Merck Index indicates that 10 mg of guanidine,
CH5N3, may be administered for each kilogram of body
mass in the treatment of myasthenia gravis. The nitrogen
in a 4-tablet sample that had a total mass of 7.50 g was
converted to ammonia by a Kjeldahl digestion, followed
by distillation into 100.0 mL of 0.1750 M HCl. The
analysis was completed by titrating the excess acid with
11.37 mL of 0.1080 M NaOH. How many of these
tablets represent a proper dose for a patient who weighs
(a) 100 lb, (b) 150 lb, and (c) 275 lb?

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