00. y-valerolactone + 2 equivalents of methylamine1. React the carbonyl compound:It is (circle one) CONJUGATEDNON-CONJUGATEDThe Nucleophile isPotential to Establish a Resonance SystemOption 1: Almost all reactionsOption 2: When Nu is a strong base (OH or OR),1 (Preferred)and the leaving group is identical to the NuNUBCircle the option and reasonOption 1: Always use UNLESSOption 2: (Remove the a H)The Nu matches Y AND is -OR2. Take care of the negative formal charge of the oxygen in the tetrahedral complexOption 1 (Preferred): All cases except Option 21 (Preferred)Option 2: If there are no leaving groups,R-or if the only potential leaving group isthe Nu that was just added and itis not a very good leaving group (N or O).Circle the option and reasonOption 1: Always use UNLESSOption 2: There is no leaving group (there areonly carbons and hydrogens), OR there are onlycarbons and hydrogens except for the Nu thatjust added, AND the Nu is N or O.If the double bond is reformed, what criterion is used to select the leaving group? (circle one)ShellsElectronegativityEWA/ResonanceCharge3. If a hydrogen atom is added instead, does the reaction continue? Yes NoXs or8- HÖ-HR--C8+-R8- Nu

In this reaction nucleophile is amine . First NH2 attack on carbonyl carbon and then π bond transfer…

The Nucleophile is Potential to Establish a Resonance System Option 1: Almost all reactions R- Option 2 When Nu is a strong base (OH or OR). 1 (Preferred) and the leaving group is identical to the Nu NUB Circle the option and reason Option 1: Always use UNLESS Option 2: (Remove the a H) The Nu matches Y AND is -OR are of the negative formal charge of the oxygen in the tetrahedral complex Option 1 (Preferred): All cases except Option 2 1 (Preferred) Option 2: If there are no leaving groups, or if the only potential leaving group is the Nu that was just added and it is not a very good leaving group (N or O). R Circle the option and reason Option 1: Always use UNLESS Option 2: There is no leaving group (there are only carbons and hydrogens), OR there are only carbons and hydrogens except for the Nu that just added, AND the Nu is N or O. ble bond is reformed, what criterion is used to select the leaving group? (circle one) Electronegativity EWA/Resonance Charge

The Nucleophile is Potential to Establish a Resonance System Option 1: Almost all reactions R- Option 2 When Nu is a strong base (OH or OR). 1 (Preferred) and the leaving group is identical to the Nu NUB Circle the option and reason Option 1: Always use UNLESS Option 2: (Remove the a H) The Nu matches Y AND is -OR are of the negative formal charge of the oxygen in the tetrahedral complex Option 1 (Preferred): All cases except Option 2 1 (Preferred) Option 2: If there are no leaving groups, or if the only potential leaving group is the Nu that was just added and it is not a very good leaving group (N or O). R Circle the option and reason Option 1: Always use UNLESS Option 2: There is no leaving group (there are only carbons and hydrogens), OR there are only carbons and hydrogens except for the Nu that just added, AND the Nu is N or O. ble bond is reformed, what criterion is used to select the leaving group? (circle one) Electronegativity EWA/Resonance Charge

Organic Chemistry: A Guided Inquiry

2nd Edition

ISBN:9780618974122

Author:Andrei Straumanis

Publisher:Andrei Straumanis

Chapter14: Elimination

Section: Chapter Questions

Problem 23E

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