The pedigree for Queen Victoria of England, acarrier of hemophilia A, shows the transmission tosome of her descendants, including members ofmany royal families in Europe, such as Russia andSpain, but not Germany. Hemophilia A does notaffect anyone in the present British royal family.Can you explain why hemophilia A hasdisappeared from one family and appeared inothers?

The pedigree for Queen Victoria of England, acarrier of hemophilia A, shows the transmission tosome of her descendants, including members ofmany royal families in Europe, such as Russia andSpain, but not Germany. Hemophilia A does notaffect anyone in the present British royal family.Can you explain why hemophilia A hasdisappeared from one family and appeared inothers?

Human Biology (MindTap Course List)

11th Edition

ISBN:9781305112100

Author:Cecie Starr, Beverly McMillan

Publisher:Cecie Starr, Beverly McMillan

Chapter19: Introduction To Genetics

Section: Chapter Questions

Problem 7CT

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In humans, a rare dominant disorder known as nail-patella syndromecauses abnormalities in the fingernails, toenails, and kneecaps.Researchers have examined family pedigrees with regard to thisdisorder and have also examined the blood types of individualswithin each pedigree. (A description of blood genotypes is foundin Chapter 4.) In the following pedigree, individuals affected withnail-patella disorder are shown with filled symbols. The genotypeof each individual with regard to ABO blood type is also shown.Does this pedigree suggest any linkage between the gene thatcauses nail-patella syndrome and the gene that causes blood type?
Below is a partial pedigree of hemophilia in the British RoyalFamily descended from Queen Victoria, who is believed to bethe original “carrier” in this pedigree. Analyze the pedigree andindicate which females are also certain to be carriers. What is theprobability that Princess Irene is a carrier?
A man whose father was hemophilia, but whose own blood clotting time is normal, marries a women with no record of hemophilia in her pedigree. What is the chance of hemophilia in their children?
Victoria’s youngest child, Beatrice, gave birth to one daughter, one normal son, and two hemophilic sons. **Based on the pedigree, Alfonso XIII of Spain is phenotypically normal. Does that mean he received the normal gene from Beatrice? Why or Why not?**
Below is the pedigree of one form of hemophilia. Which type of hemophilia can you rule out? (You should try to write out the genotype of each individual to see whether you can rule one out)
Xias father has type B blood (lBi) while her mother has type A (lAi) blood. What are the possible blood types of Xia and her two brothers?
Is it possible for any sonof a couple formed by ahemophilic man (XhY) and anonhemophilic noncarrier(XX) woman to be hemophilic?
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