The phosphate buffer (H₂PO4¹ HPO42 + H¹) in esophageal cells has a pKa of 7.2. If acid floods into -1 -2 cells, and the pH drops from 7.2 to 3.2, which concentration in the cells will increase, H₂PO4¹ or HPO4 2? Is pH 3.2 in the buffer range of this phosphate buffer (pKa 7.2)? Esophagus Stomach HPO4²; no HPO4²: yes H₂PO4¹; yes H₂PO4-¹: no

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter11: The Blood
Section: Chapter Questions
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The phosphate buffer (H2PO4 HPO42+ H") in esophageal cells has a pKa of 7.2. If acid floods into
cells, and the pH drops from 7.2 to 3.2, which concentration in the cells will increase, H2PO4 or HPO42?
Is pH 3.2 in the buffer range of this phosphate buffer (pKa 7.2)?
Esophagus
Stomach
HPO42, no
HPO4: yes
H,PO4: yes
H,PO41; no
Transcribed Image Text:The phosphate buffer (H2PO4 HPO42+ H") in esophageal cells has a pKa of 7.2. If acid floods into cells, and the pH drops from 7.2 to 3.2, which concentration in the cells will increase, H2PO4 or HPO42? Is pH 3.2 in the buffer range of this phosphate buffer (pKa 7.2)? Esophagus Stomach HPO42, no HPO4: yes H,PO4: yes H,PO41; no
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