CYP2E1 has a much higher Km for ethanol than ADH (11 mM versus 0.05 mM, respectively). When greater portions of ethanol are ingested (0.08% or 17 mM), which part of the statement would be true?

Q: If this molecule can inhibit toxic effects at 0.5mM against gastric carcinoma cells, does it mean…

A: IC50 is the concentration at which 50% inhibitory effect is observed.

Q: In what general ways is balance of Ca21 achieved in the blood?

A: Calcium is of crucial importance in our body. It has several roles to play such as-  Contraction…

Q: Based on the principles of RP-HPLC, which sub fraction in the figure (P1 to P8) is the most polar?…

A: HPLC (High Performance Liquid Chromatography): This method is used for protein purification. Here…

Q: What is the difference between MIC and MBC and how can you determine these?

A: The MIC is the least concentration of your medication that represses bacterial development so you…

Q: What does the fact that the two histograms overlap as much asthey do indicate about the extent to…

A: Introduction  PCSK-9 (Proprotein convertase subtilisin-like kexin type 9) is newly discovered serine…

Q: a protein collected through affinity chromatography displays no activity even though it is found to…

A: Protein is made up of one or more amino acids that are linked together to form a chain. The building…

Q: What method might be used to determine the extent of binding of hemin to the 3 NEAT domains of Hbp2?

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A: Alarmones are the intracellular molecules produced by the prokaryotes like bacteria and Archaea…

Q: through cell membranes, explain why all cell types are not sensitive to the presence of 17 beta

A: 17 beta estradiol is formed in the ovaries, testes or adrenal glands. It is made from cholesterol.

Q: Compared to adult Hb (HbA), fetal Hb (HbF) has one less histidine in the central cavity where BPG…

A: Humans have both Hb A and Hb F hemoglobin which are present in adult and fetal life respectively.…

Q: Give the normal value of CRP (C-Reactive Protein). Why is CRP significant? Is CRP specific to one…

A: Our immune system is responsible for production of different proteins that are involved in immune…

Q: Would the following alterations to Src be oncogenic? Explain. (a) The mutation of Tyr 527 to Phe.…

A: Tyrosine kinases are an important subgroup of cellular receptors that play an important role in…

Q: what is the standard of FTIR in pectin?

A: Infrared spectroscopy analyses the samples by infrared spectrum. The infrared absorption of…

Q: Is fadh2 oxidized or reduced?

A: FADH2 is a coenzyme which is used in cellular respiration process to make fuel from food into…

Q: Describe the steps of TH2 activation in 2- 3 paragraph

A: CD4 T helper cells are the major contributors in the adaptive immune system. They were first…

Q: After three minutes, the concentration of drug Zip in the red blood cells is 10 mmoles l-1. What is…

A: The rate of reaction is the rate of change of concentration of a reactant or product with time, then…

Q: Approximate P50 for myoglobin from its binding curve. Approximate P50 for normal hemoglobin and the…

A: P50 is the oxygen tension or the pressure of oxygen at which hemoglobin or other oxygen binding…

Q: Assume that the binding of one molecule of epinephrine to a seven-transmembrane helix (7TM) receptor…

A: Epinephrine is an amino acid-derived hormone. After its release from the adrenal gland, it travels…

Q: 1) Draw a chromatogram depicting separation of proteins 1, 2, and 3 (protein #1, mw 30,000, protein…

A: The diagram of chromatograph  is as follows-

Q: The alpha subunit of the heterotrimeric G-protein complex becomes activated upon activation of a…

A: Introduction: G Protein-coupled receptor (GPCR) also known as serpentine receptors or seven-pass…

Q: At what concentration of S(expressed as a multiple of KM) will νo=0.95Vmax?

A: The enzyme catalyzed reaction is a biochemical reaction involving conversion of substrate molecules…

Q: Deficiencies of the components of Complexes I, III, and IV tend to have severe physiological…

A: The complex I, II, III, IV, and V are the cytochrome complexes that are part of the oxidative…

Q: What enzyme is missing in the Ahxk2 cells, and what reaction does the enzyme catalyze?

A: Wild type cells are usually considered as dominant. Here wild type cells (white) and hexokinase…

Q: What is the biological function of the Neurofibromin-1 (NF1) protein?

A: The Neurofibromin gene is a tumor suppressor gene (TSG). It is located on chromosome 17 long arm. It…

Q: Based on your Lineweaver-Burk plot, what is the mode of PaESBL-1 inhibition by NSAMB?

A: Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: Which of the following dephosphorylates PI 3,4,5-trisphosphate, thereby blocking the activation of…

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Q: Many species have a third type of LDH subunit that is found predominantly in the testes. If this…

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Q: What is the total APC payment for HCPCS codes 66984, 71020, and 78740? Round the answer to two…

A: Given,  APC weight 24.56 Conversion factor CF $80.79 Wage Index 0.9445 AS PER the OPPS formula :…

Q: A.What is the Result of the sodium potassium ATPase activity in the cell? B.What mechanism does the…

A: The plasma membrane contains the sodium-potassium pump.

Q: of Covid-19 by rec

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Q: What are the two reactions that control densities of RGD and VEGF respectively? Draw the reactions…

A: Answer of the question given below...

Q: What enzyme(s) control the total levels of cGMP in a cell? Is guanylyl cyclase one of the enzymes?

A: Cyclic GMP or cGMP is a second messenger molecule during the process of signal transduction.

Q: Why Valinomycin is highly selective for K+ relative to Na+?

A: Valinomycin is a naturally occurring dodecadepsipeptide used in the transport of potassium and as an…

Q: What is the dominant biochemical activity or molecular interaction that Sickle Cell Anemia…

A: Hemoglobin is an oligomeric conjugated protein with four peptide chains joined by a…

Q: What would be the effect of adequate concentration of AMP andGMP?

A: AMP: Adenosine Monophosphate GMP: Guanosine Monophosphate

Q: Briefly explain how heme regulates the expression of globin genes in cells that synthesize…

A: Hemoglobin synthesis are global production and heme synthesis. Globin chain production occurs in the…

Q: What is the connection between the absence of HGPRT activity and the behavior al characteristic s of…

A: Lesch Nyhan syndrome (LNS) is aware inborn error of purine metabolism, characterized by the absence…

Q: What will be the preferred mechanism of transportation to ER by the proteins associated with RER?

A: The endoplasmic reticulum is the largest organelle of the cell, extending its network of membrane…

Q: Differentiate HbA1c from Fructosamine. Give 3 comparisons

A: HbA1c- it is the hemoglobin test which measures the amount of sugar in the blood which is attached…

Q: If you were to remove the ER retrieval signal fromprotein disulfide isomerase (PDI), which is…

A: We got the information of first type in carboxyl terminus of soluble ER proteins and in golgi…

Q: What do the peaks of C6H12O2 show?

A: The peaks of the substance under study are obtained after using the bio technique f NMR. Nuclear…

Q: why is there a difference between the stock solution concetration of chymotrypsin calculated from…

A: Stock concentration is the concentration of biomolecule which is prepared and dilutions where done…

Q: Could you please help answer this question?

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Q: Determine the cause-effect relationship of the following variables given. Choose the best answer…

A: Xanthine oxidase is an enzyme that is involved in the oxidation of hypoxanthine to xanthine and…

Q: who is most at risk of shiver illness from covid-19?

A: Coronavirus disease is caused by SARS CoV-2 virus. The virus affects the respiratory system that…

Q: A quanta holds about 10,000 molecules of ACh.  How many quanta are exocytosed during a single…

A: Introduction Synaptic potential refers to the electric potential across the postsynaptic membrane…

Q: A protein (PrX) was heated in vitro to 45C for 15 min, in the presence or absence of Hsp40, Hsc70,…

A: Hsp40 and Hsc70 are the molecular chaperones or heat-shock proteins. Molecular chaperones help the…

Q: Describe the role of pH in regulating the interaction between mannose 6-phosphate and the M6P…

A: The term pH stands for hydrogen potential. It is been stated that they are defined to decide whether…