The substituted pyridine shown below will undergo nuclophilic substitution at one position. Predict the product and draw a curved arrow mechanism for the reaction. Show the most important resonance form for the all important tetrahedral intermediate. There may be some variation in correct answers, but to match Wolfie's solution draw four arrows, then the tetrahedral intermediate followed by four more arrows and the final product. Br 8-CH3 Create OscerSketch Answer 1

The substituted pyridine shown below will undergo nuclophilic substitution at one position. Predict the product and draw a curved arrow mechanism for the reaction. Show the most important resonance form for the all important tetrahedral intermediate. There may be some variation in correct answers, but to match Wolfie's solution draw four arrows, then the tetrahedral intermediate followed by four more arrows and the final product. Br 8-CH3 Create OscerSketch Answer 1

Organic Chemistry

9th Edition

ISBN:9781305080485

Author:John E. McMurry

Publisher:John E. McMurry

Chapter11: Reactions Of Alkyl Halides: Nucleophilic Substitutions And Eliminations

Section11.SE: Something Extra

Problem 37MP

See similar textbooks

Similar questions

2- Mention the product of a nucleophilic substitution reaction of (S)-2-bromohexane with acetate ion, CH3CO2- Assume that inversion of configuration occurs, and show the chemistry of both the reactant and product. 3- Draw the mechanism of the SN2 Reaction. Show the correct directions of the arrows, and all reagents. 4- Draw the mechanism of the SN1 Reaction. Show the correct directions of the arrows, and all reagents. 5- Draw the mechanism of the E2 Reaction with an Alkyl Halide. Show the correct directions of the arrows, and all reagents. 6- Draw the mechanism of the E1 Reaction with an Alkyl Halide. Show the correct directions of the arrows, and all reagents. 7- Mention the product formed in an SN2 reaction between 1-bromobutane and NaI. 8- Rank the following compounds in order of their expected reactivity toward SN2 reaction: CH3Br, CH3OTos, (CH3)2CHCl. 9- Explain Grignard Reagents in details with one example. 10- Mention how a halogen substituent can be replaced by a deuterium atom…
When 2-bromo-3-phenylbutane is treated with sodium methoxide, two alkenes result (by E2 elimination). The Zaitsevproduct predominates.(a) Draw the reaction, showing the major and minor products
Terminal alkynes react with Br2 and water to yield broom ketones. Propose a mechanism for the nomination reaction below and provide the IUPAC name of the product.
Predict the product(s) you would expect from treatment of each compound with (1) dilute,neutral KMnO4 and (2) warm basic KMnO4, then dilute acid.(a) hex-1-yne (b) hex-2-yne (c) hex-3-yne(d) 2-methylhex-3-yne (e) cyclodecyne
20. (a) Show all steps in the synthesis of 2-pentene from 2-bromopentane. Show the structure of all reactants and product. CH3CHBrCH2CH2CH3 -------> CH3CH=CHCH2CH3 (b) Correctly identify the mechanism in (a) above(SN2, SN1, E2, E1)
Rank the nucleophiles in each group in order of increasing nucleophilicity. a.−OH, −NH2, H2O b.−OH, Br−, F− (polar aprotic solvent) c.H2O, −OH, CH3CO2−
15.4 (jkl) Predict the major product or reagent that completes the transformation
Provide the mechansim using curved arrows of the reaction of p-t-butyl phenol treated with acetic anhydride in AlCl3. Include resonance stabilized intermediates and if more than one product is formed, label them as major, minor, etc. thank you for the help
Which alkene is major product of the E2 reaction below? Options: 1 2 3 4
Show the major organic product and mechanism for the transformations below.
Propose an efficient synthesis of the following compound starting from benzene and any other necessary reagents. Show all stable products leading up to the target compound. Thank you!
These reagents can produce ketones with alkynes A. BH3, THF, H2O2 B. KMnO4 C. O3 D. H2SO4, H2O, HgSO4 choices:A,DB,CA,B,CA,B,C,D