There are two classes of MHC molecules with distinct subunit compositions but similar three-dimensional structures. Both MHC class I and MHC class II molecules are highly polymorphic genes in the human population, with tens to hundreds of different alleles co-existing in the population. This means that a comparison of the MHC protein sequences between two individuals would reveal amino acid differences between one individual and the next. However, these amino acid differences are not randomly distributed along the entire protein, but are clustered in certain locations. In the figure below, the diagram that most correctly indicates the regions of greatest variability between different MHC proteins (shown by the red highlights) is:
There are two classes of MHC molecules with distinct subunit compositions but similar three-dimensional structures. Both MHC class I and MHC class II molecules are highly polymorphic genes in the human population, with tens to hundreds of different alleles co-existing in the population. This means that a comparison of the MHC protein sequences between two individuals would reveal amino acid differences between one individual and the next. However, these amino acid differences are not randomly distributed along the entire protein, but are clustered in certain locations. In the figure below, the diagram that most correctly indicates the regions of greatest variability between different MHC proteins (shown by the red highlights) is:
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