These are performance curves for two oxygen binding proteins. While we didn't go over the curves themselves in lecture, what are the axis labels? 1.0 0.8 0.6 0.4 0.2 Myoglobin Hemoglobin P50 = 26 torr
Q: A complementation test can be used to determine the mode of inheritance of a mutant allele O whether…
A: Since you have posted multiple questions, we will provide the solution only to the first question as…
Q: Describe the membrane junctions of cells which are important in cell to cell communication.
A: Cell junctions can be described as the class of cellular structure which contains the multi protein…
Q: A) What conclusions can you draw about the gene, alleles, and gene function from these results? B)…
A: AVT plays a role in a number of physiological processes connected to osmoregulation and…
Q: Epigenetic marks regulate gene expression. Which epigenetic mark is NOT associated with positive…
A: These are chemical modifications that change the gene expression, make it on or off
Q: Describe the difference between white and gray matter structure and distribution in the brain.
A: White matter and gray matter in the brain have different compositions and appearances. White matter…
Q: Complete the following chart to calculate the population growth rates for a population of rats…
A: Exponential growth can occur when there are few people and plenty of resources. But this is not the…
Q: Match each figure to the correct descriptive term. Answer choices may be used only once. Not all…
A: The morphology of bacteria refers to their physical shape and structure. Bacteria exhibit a wide…
Q: 1.3.1 In each of the research situations below, describe whether the researcher is conducting an…
A: Researchers use a variety of methodologies tailored to their specific objectives in their quest to…
Q: 1) Many organisms have the ability to reproduce asexually as well as perform sexual reproduction. A…
A: The Hardy-Weinberg equilibrium principle may be used to calculate the equilibrium frequency of men…
Q: Provide a brief description of the three macronutrients: carbohydrate, protein, and fat. Explain the…
A: The body needs certain compounds called nutrients in order to operate properly. Macronutrients and…
Q: 1. A study published in BMC Health Services Research in October 2008 considered the cost-…
A: The following is the program's cost-benefit analysis:· Each patient in the program is charged…
Q: Queen Victoria had 1 (Leopold) out of four male offspring with hemophilia. What was the probability…
A: Mutations in the genes that produce certain clotting factors (clotting factor VIII for haemophilia A…
Q: Your lazy labmate needs your help! They set up a 10-ml culture of the slow-growing Myxococcus…
A: Answer.) :- To calculate the required cell density for the new culture, you can use the…
Q: Which of the following would most likely occur if an electrical stimulus were applied at point C in…
A: The neurons have the capability to generate and propagate electrical impulses and it is known as…
Q: A O 1 2 3 456 7 8 9 CG site number 1 2 3 4 5 6 7 8 9 CG site number *p<0.05 ##p<0.01 The viable…
A: The study discussed in the question examines the impact of BPA exposure on the methylation of the…
Q: A bacterium that does not have all the enzymes of central metabolism: O Can produce all the…
A: Answer.):- Bacterial meta bolism is a complex process involving various enzymatic reactions that…
Q: SCIENTIFIC METHOD AND LABORATORY PROTOCOL Critical Thinking and Review Questions 1. In your own…
A: Scientific knowledge helps us to understand the natural world and its phenomena existing around us.…
Q: Shown (the picture) is a partial gene map for Drosophila melanogaster. In Drosophila, vermillion…
A: Gregor Mendel was an Austrian scientist, mathematician, and biologist who proposed laws of…
Q: 36. the diploid somatic nucleus of xenopus has 900 copies of rDNA and in the mature oocyte it could…
A: The correct option is (b) transcriptional controlThe increase in rDNA (recombinant DNA) copies from…
Q: Create a phylogenic tree for the following organisms: Glomus Spirogyra Entamoeba Radiolarian…
A: Phylogenetics is significant since it develops our understanding of the evolution of genes, genomes,…
Q: 14. Which mutation would be more harmful to a cell? For each predict the outcome of each mutation…
A: In order to base-pair with the correct codon on the mRNA during protein synthesis, the anticodon is…
Q: 3. According to Dr. Kubler-Ross, which stage of grief is the patient experiencing? O a. anger 4 O b.…
A: From the given options, the answer can be both A. AngerC. depressionFor more accurate answer you…
Q: Breakdown of the items in the image can occur through an anaerobic process to generate a renewable,…
A: In the absence of oxygen, bacteria utilize anaerobic digestion to break down organic materials,…
Q: a Spike-6P C count RBD-Fc S1-Fc d 8 3 S MFI 250 200- 150- 100- 1 50- Ace2 Gapdh S1 RBD 319 -S1- 541…
A: A vital component of the renin-angiotensin system, angiotensin-converting enzyme 2 (ACE2) acts as…
Q: Put the following in order of how much energy they generate given a constant starting amount of…
A: Answer.):-When it comes to generating energy from glucose, different biological processes play a…
Q: 1. Draw an accurate segment of DNA with its complimentary strand. (10 points) Make sure to include…
A: DNA (Deoxyribose :Only acts as genetic material.Polynucleotide (monomeric unit is…
Q: I. II. III. 1-4 1 1-1 ✓ [Select] 2/3 0 1 1/2 11-3 [Select] 1 II-4 [Select] 2 2 3 1 This pedigree…
A: Q.Ans:- Autosomal recessive trait:- These are traits that show their effect only when the alleles of…
Q: o activate your adaptive defense immune system, you must be: Select one: a. Exposed to the…
A: The immune system of the kid defends their body from external threats. These include pathogens like…
Q: A population has 100 homozygous dominant individuals (AA), 372 heterozygous individuals, and 40…
A: Population genetics is a field of study that examines the genetic structure of populations and how…
Q: Question 4 options: bacillus aggregation spiral coccus diploid
A: The morphology of bacteria refers to their physical shape and structure. Bacteria exhibit a wide…
Q: a. In order to help you visualize the processes, begin by drawing the 4 pictures from question "2"…
A: Cell cycle is defined as a series of events which involves DNA replication and the formation of two…
Q: Plants vary widely in how they allocate biomass to roots, leaves and stems. Two key measures of…
A: the root-to-shoot ratio reflects the allocation of resources between belowground and aboveground…
Q: Hemoglobin from the Galapagos tortoise is 64% identical to that from human beings. In contrast, a…
A: Evolution is a natural, continuous process by which species adapt to their natural habitats and as a…
Q: Question 30 1 pts While walking barefoot along the beach, you step on a shard of glass and…
A: Q 30.) :- ans.When you step on a shard of glass, your body's automatic response is to protect itself…
Q: I Use colored pens or pencils to shade in both the figure and the labels. Each meral following the…
A: The heart is an important organ of the body that helps in circulation of the oxygen-rich blood…
Q: The conformational change of retinal, from the cis to trans configuration, indirectly: O…
A: The conformational change of retinal, from the cis to trans configuration, is a crucial event in…
Q: Menstruation occurs when there is a decrease in levels of estrogen and progesterone. levels of FSH…
A: The menstrual cycle is the process occuring in the female reproductive system. In this process,…
Q: researcher wants to compare the pathogenicity of a mutant pathogen relative to wild type in an…
A: The term "pathogenicity" describes an organism's capacity to cause disease in its host. The overt…
Q: Suppose that a person with cancer has the following options: Do nothing: spend nothing and live two…
A: The cost of doing nothing is zero dollars, and the QALY (quality-adjusted life year) is equal to…
Q: Please write a summary of cancer disease of cat • talk about why did you choose this disease to…
A: Cancer in cats: Cat cancer is also known as feline cancer which is a complex and varied group of…
Q: Which method of counting cells would you use for each of these situations? Viable Cell Count Optical…
A: In microbiology counting bacterial cells is an important technique for several research and…
Q: Urine creatinine: 190 mg/dL .Plasma creatinine: 2.5 mg/dL. 24-hour urine collection: 975 mL.…
A: Creatinine clearance is a measure used to estimate how well the kidneys are functioning. It…
Q: 2. Divisions of Science; Branches of Biology; Branches of Branches and Allied Sciences
A: Science is a broad field that comprises various branches and disciplines. It involves the pursuit of…
Q: Why are indices better than simple measurements for comparing fossil specimens
A: In the intricate world of paleontology, where the remnants of ancient life hold invaluable clues to…
Q: The phylogenetic tree below depicts the evolutionary relation among a subset of ants. The Taxa…
A: These groups are also known as clade. This includes a group of organisms that has a common ancestor.…
Q: Solve the following problems involving changes in patient part size. a. A satisfactory radiograph is…
A: The kVp and mAs are two of the most important exposure factors in radiography.The kVp controls the…
Q: What is H9 shown on the figure is? What so you think the methylation is higher or lower in the IMR90…
A: Differentially methylated regions (DMRs) in the genome have been identified and linked to a variety…
Q: Question 24 The primitive streak in a bird embryo is the functional equivalent to which of the…
A: The primitive streak is a transient structure that forms during early embryonic development in…
Q: Post synaptic neurons membrane potentials are less negative than resting membrane potentials when…
A: Post-synaptic neurons are the neurons that receive signals (in the form of neurotransmitters) from…
Q: 1. How many TSS sites were identified using this technique? 2. Look at the labels next to each of…
A: The precise nucleotide position in a DNA or RNA sequence where the translation of an mRNA molecule…
Trending now
This is a popular solution!
Step by step
Solved in 3 steps
- If instead of using 3.5 µM myoglobin (receptor) you used half of this (that is, 1.75 µM myoglobin), what would be that value of the Kd, that you calculated ( how would it change)? Please explain so I can solve on my own :) (How does changing concentration of the receptor in a ligand-receptor binding experiment affect the dissociation constant?)From the figure of O2 binding to myoglobin and hemoglobin (ignore the linemarked as T) as described in lecture (shown below) answer the following questions. a) Estimate the P50 for myoglobin from the plot. Show how this estimation isdetermined from the binding curve above. ( The first ghraph) b)Using YO2 = PO2/P50 + PO2 , calculate the fraction of O2 bound for myoglobin at 1 torr. (2nd graph) c)Using the binding curve on the previous page, show how you can estimate whatfraction of hemoglobin is bound near tissues at a pO2 of 30 torr and provide this value. If the pH were lowered, will the amount of O2 bound to hemoglobin at 30 torr increaseor decrease? Explain why this is so based on how this changes hemoglobin structure. If 2,3-BPG were added to the solution, will the amount of O2 bound to hemoglobin at30 torr increase or decrease? Explain why this is so based on how this changes hemoglobinstructure.Heart and muscle cells, where myoglobin resides, maintains an intracellular pO2 of about 2.5 torr. Calculate the fractional saturation (for human myoglobin) if a small change (1 torr) in oxygen partial pressure occurs in either direction (ie what happens at 1.5 torr, what happens at 3.5 torr?) and explain how a small change in oxygen pressure dramatically changes the myoglobin oxygen binding.
- 1. a. In active muscle cells, the pO2 is about 10 torr at the cell surface and 1 torr at the mitochondria(the organelles where oxidative metabolism occurs). Calculate the percentage of bound oxygentransported to the mitochondria of muscle cells by myoglobin (KD = 2 torr). b. A new oxygen transport protein that exhibits cooperative binding has been isolated and is beingstudied in the lab. Calculate the KD value if Y = 0.76 when pO2 = 18 torr (assume n = 2.5). Howdoes this compare to the KD value for hemoglobin? Does this protein bind more or less tightly tooxygen compared to hemoglobin?a) What is the KDD for this myoglobin variant? b) What is the predicted fractional saturation for the last box in the table? (please show your work so I can better understand) c) What is unexpected about the binding curve above? (5 words or less) d) What must be structurally different about this new variant relative to other known Myoglobin variants to generate this graph?Given: Beer-Lambert Law A = Ecl E = 8000 for Met myoglobin E= 14,000 for oxy-myoglobin l=1 cm find c, the concentration of Oxy-Mb and Met-Mb based on the data table given below.
- Theoretically, the pI of myoglobin is 7.2. In phosphate buffer pH 6.0, what is the overall charge of myoglobin? How would it interact with CM Sepharose?A new oxygen transport protein that exhibits cooperative binding has been isolated and is beingstudied in the lab. Calculate the KD value if Y = 0.76 when pO2 = 18 torr (assume n = 2.5). Howdoes this compare to the KD value for hemoglobin? Does this protein bind more or less tightly tooxygen compared to hemoglobin?How does one measure Km using a Lineweaver-Burk plot? 1. By determining the reciprocal of the y-intercept 2. By determining the negative reciprocal of the x-intercept 3. By determining the slope and multiplying it by kcat 4. By determining the saturation point
- Approximate P50 for myoglobin from its binding curve. Approximate P50 for normal hemoglobin and the hemoglobin mutant from the binding curve. At low pO2 (below 20 Torr), which binds O2 with greater affinity, normal hemoglobin or the hemoglobin mutant? At high pO2 (above 30 Torr), which binds O2 with greater affinity, normal hemoglobin or the hemoglobin mutant? Which protein, normal hemoglobin or the hemoglobin mutant, transports O2 more efficiently? Briefly explain your answer.Neutral sphingomyelinase 2 converts sphingomyelin into ceramide and phosphorcholine. What kind of enzyme is it? Assume Vmax is 35 µM min-1. When you provide 3.0 x 10-5 M of sphingomyelin, you observe an initial velocity of 6.0 µM min-1. Calculate the KM.In order to improve contract during X-ray diagnostics of soft tissues, contrast agents are used. For example, the stomach and intestines are filled with barium sulphate ВаSO4. Compare mass attenuation coefficients for soft tissues and for barium sulphate.