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- Describe the effects of the mutation causing the p21 promoter to no longer bind p53 on cell signaling pathways and metabolism or cell cycle control."In most differentiated tissues, daughter cells retain a memory of gene expression patterns that were present in the parent cell through mechanisms that do not involve changes in the sequence of their genomic DNA" is true or false.Describe an example of a pathological condition that results in mutants genes that control expression of the inducer or components of its pathway. Inducing Factor Signal Transduction Pathway and Components Developmental Functions and Target Cell/Tissue Associated Pathologie 1. Hedgehog 2. EGF
- The product of the human papillomavirous oncogene E7promotes cancer by emhancing expression of telomere inhibiting DNA damage repair pathways binding to Rb protein and preventing itd function ubiquitinating the tumor suppressor p53Describe an example of a pathological condition that results in mutants genes that control expression of the inducer or components of its pathway. Inducing Factor Signal Transduction Pathway and Components Developmental Functions and Target Cell/Tissue Associated Pathologies Hedgehog EGFEpigenesis relating to genetics refers to which of the following A. Genetic information is limited to what we inherit only from our biological parents. B. Genes are not influenced by environmental factors. C. Genes we inherit are fully expressed at birth. D. Genes are turned on or off as needed, by the developing body or environmental triggers, across the life-span
- describe the relationship between a proto-oncogene and an oncogene, and explain how one arises from the other. Explain how a mutation in the EGF receptor, or in a GTP- binding protein, can lead to unregulated cell division.Describe three types of genetic changes that commonly convert aproto-oncogene to an oncogene. Explain how the genetic changesare expected to alter the activity of the gene product.Which mechanisms for regulating gene expression may be applied for the treatment of such diseases? Propose a method of treatment. Explain how it might work. Reference: https://link.springer.com/article/10.1186/ar3317