Consider the mechanism for the hydrolysis of the ester shown below. Identify the false statement. H2O CH,COCH, CH,CO,H + CH,OH a

Organic Chemistry: A Guided Inquiry
2nd Edition
ISBN:9780618974122
Author:Andrei Straumanis
Publisher:Andrei Straumanis
Chapter26: Aldol And Claisen Reactions
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Question 16
Consider the mechanism for the hydrolysis of the ester shown below. Identify the false statement.
H20
CH,COCH,
CH,CO,H + CH,OH
Under acidic conditions, the first step is protonation of oxygen a to create a good leaving group.
Under acidic conditions, the process is reversible.
The process requires a catalyst because water is a weak nucleophile.
Under basic conditions, the process is irreversible because of the formation of carboxylate anion.
Transcribed Image Text:Question 16 Consider the mechanism for the hydrolysis of the ester shown below. Identify the false statement. H20 CH,COCH, CH,CO,H + CH,OH Under acidic conditions, the first step is protonation of oxygen a to create a good leaving group. Under acidic conditions, the process is reversible. The process requires a catalyst because water is a weak nucleophile. Under basic conditions, the process is irreversible because of the formation of carboxylate anion.
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