Very few testing procedures are absolutely perfect. This has become particularly apparent with the discussion of sensitivity and specificity of COVID-19 Rapid Antigen (RAT) tests recently. These have often been compared to the gold standard Polymerase Chain Reaction (PCR) test. The information booklet for a high quality RAT test provides details for sensitivity and specificity. RAT tests were applied to 101 subjects who where known to have COVID-19. Of those, 91 resulted in a positive RAT test. Another 305 subjects who were known not to be infected with COVID-19 were tested using the RAT test and 303 of them tested negative. Looking on the NSW Health Website, there are currently 166,957 active cases of COVID-19 in NSW out of a population of 8,160,000 people. Let C be the event that someone has COVID-19 and therefore Ccis the event that someone does not have COVID-19. Let P be the event that someone tests positive for COVID-19 and therefore P cis the event that someone tests negative for COVID-19. (b) Given someone has COVID-19, find the probability that a test will yield a positive result. (This probability represents the sensitivity of the test.) (c) Given someone does not have COVID-19, find the probability that the test will yield a negative result. (This probability represents the specificity of the test.) (d) Construct a tree diagram for the above scenario. Clearly label the arms representing sensitivity and specificity.

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Very few testing procedures are absolutely perfect. This has become particularly apparent with the
discussion of sensitivity and specificity of COVID-19 Rapid Antigen (RAT) tests recently. These
have often been compared to the gold standard Polymerase Chain Reaction (PCR) test.
The information booklet for a high quality RAT test provides details for sensitivity and specificity.
RAT tests were applied to 101 subjects who where known to have COVID-19. Of those, 91 resulted
in a positive RAT test. Another 305 subjects who were known not to be infected with COVID-19
were tested using the RAT test and 303 of them tested negative.
Looking on the NSW Health Website, there are currently 166,957 active cases of COVID-19 in NSW
out of a population of 8,160,000 people.
Let C be the event that someone has COVID-19 and therefore Ccis the event that someone does
not have COVID-19. Let P be the event that someone tests positive for COVID-19 and therefore
P cis the event that someone tests negative for COVID-19.

(b) Given someone has COVID-19, find the probability that a test will yield a positive
result. (This probability represents the sensitivity of the test.)


(c) Given someone does not have COVID-19, find the probability that the test will yield
a negative result. (This probability represents the specificity of the test.)


(d) Construct a tree diagram for the above scenario. Clearly label the arms representing
sensitivity and specificity.

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