What causes regular cocaine users to chose that "initial high"?

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Chapter13: Nerves Of Steel
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What causes regular cocaine users to chose that "initial high"?
CASE STUDY: Chocolate vs. Drugs and Dopamine
When a person eats chocolate (and enjoys it),
the initial experiences with eating the choco-
late releases dopamine levels in the brain. This
produces pleasurable and rewarding feelings in
the brain, which results in an expectation every
time chocolate is eaten. However, after a period
of time, the expectation of pleasure derived from
chocolate becomes the pleasure feeling, and
dopamine is no longer released in the brain
when chocolate is eaten.
Contrast this to when an illicit drug is taken,
let's say cocaine. Dopamine is released in the
brain, up to 10 times the normal level. These
high levels of dopamine are very rewarding and
encourage users to seek out more cocaine.
Now, unlike eating chocolate, cocaine produces
higher levels of dopamine each time it is taken,
producing more rewarding experiences and
encourages the user to take in more cocaine.
Furthermore, the brain tries to compensate for
the increase in dopamine by desensitizing the
neurons so they are not affected as easily by the
surge in dopamine. This is what creates tolerance
to the drug. Thus, after using cocaine for a period
of time, the increase in dopamine does not pro-
duce the same pleasurable feeling compared to
the first few times cocaine was used. Thus people
are constantly chasing that initial "high" and use
more of the drug, more often to gain it.
QUESTIONS TO PONDER:
1. How is dopamine affected by chocolate and
cocaine similar and different?
2. What causes regular cocaine users to chase
that "initial high"?
3. If a person who was a regular cocaine user were
to stop suddenly, do you think they would receive
pleasure from other activities that naturally pro-
duce dopamine (i.e., sex)? Justify your answer.
Source: D. Hirshman, "Your Brain on Drugs: Dopamine and Addiction."
Available at: www.bigthink.com/going-mental/your-brain-on-drugs
-dopamine-and-addiction.
Transcribed Image Text:CASE STUDY: Chocolate vs. Drugs and Dopamine When a person eats chocolate (and enjoys it), the initial experiences with eating the choco- late releases dopamine levels in the brain. This produces pleasurable and rewarding feelings in the brain, which results in an expectation every time chocolate is eaten. However, after a period of time, the expectation of pleasure derived from chocolate becomes the pleasure feeling, and dopamine is no longer released in the brain when chocolate is eaten. Contrast this to when an illicit drug is taken, let's say cocaine. Dopamine is released in the brain, up to 10 times the normal level. These high levels of dopamine are very rewarding and encourage users to seek out more cocaine. Now, unlike eating chocolate, cocaine produces higher levels of dopamine each time it is taken, producing more rewarding experiences and encourages the user to take in more cocaine. Furthermore, the brain tries to compensate for the increase in dopamine by desensitizing the neurons so they are not affected as easily by the surge in dopamine. This is what creates tolerance to the drug. Thus, after using cocaine for a period of time, the increase in dopamine does not pro- duce the same pleasurable feeling compared to the first few times cocaine was used. Thus people are constantly chasing that initial "high" and use more of the drug, more often to gain it. QUESTIONS TO PONDER: 1. How is dopamine affected by chocolate and cocaine similar and different? 2. What causes regular cocaine users to chase that "initial high"? 3. If a person who was a regular cocaine user were to stop suddenly, do you think they would receive pleasure from other activities that naturally pro- duce dopamine (i.e., sex)? Justify your answer. Source: D. Hirshman, "Your Brain on Drugs: Dopamine and Addiction." Available at: www.bigthink.com/going-mental/your-brain-on-drugs -dopamine-and-addiction.
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