What do the offspring look like? The appearance of each mouse is also called its phenotype Click Clear, and drag two white mice into the parent boxes Click Breed several times What is the phenotype of the offspriìng now? Do you think mouse offspring will always look like their parents?
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- Ancient societies used knowledge that traits are heritable in domesticating animals and developing agricultural crops. What might account for the failure to recognize that the same processes operate in humans?Explain, at the molecular level, why human genetic diseases oftenfollow a simple Mendelian pattern of inheritance, whereas mostnormal traits, such as the shape of your nose or the size of yourhead, are governed by multiple gene interactions.In cats, a temperature-sensitive allele produces the Siamese phenotype, in which the cooler extremities are dark and the warmertrunk area is lighter. A Siamese cat that spends most of its timeoutside was accidentally injured in a trap and required severalstitches in its right front paw. The veterinarian had to shave the furfrom the paw and leg, which originally had rather dark fur. Later,when the fur grew back, it was much lighter than the fur on theother three legs. Do you think this injury occurred in the hot summer or cold winter? Explain your answer
- Gregor Mendel’s basic principles of inheritance say that each trait is controlled by just one gene with just two alleles, and that each allele is clearly dominant or recessive to the other. However, we now know that many (if not most) traits are not actually inherited according to these rules. Name and describe two other (i.e., non-Mendelian) inheritance patterns, including how each one works, and a give specific example of an actual trait that follows each pattern.In a population of wild squirrels, most of them have gray fur, butan occasional squirrel is completely white. If we let P and p represent dominant and recessive alleles, respectively, of a genethat encodes an enzyme necessary for pigment formation,which of the following statements do you think is most likely tobe correct?a. The white squirrels are pp, and the p allele is a loss-offunction allele.b. The gray squirrels are pp, and the p allele is a loss-offunction allele.c. The white squirrels are PP, and the P allele is a loss-offunction allele.d. The gray squirrels are PP, and the P allele is a loss-offunction allel. Imagine you purchased an albino mouse (genotypecc) in a pet store. The c allele is epistatic to other coatcolor genes. How would you go about determiningthe genotype of this mouse at the brown locus? (Inpigmented mice, BB and Bb are black, bb is brown.)
- While traits Mendel worked with all adhered to his principles of inheritance, this is not the norm because phenotypes are typically a combination of both genetic and what other kind of influence?In humans, there is a gene called sickle-cell anemia, which produces severe anemia when homozygous recessive. The name of the disease comes from the fact that many red blood cells take on abnormal sickle shape. People homozygous recessive for this trait usually die before adulthood. Heterozygous people appear normal, but when a sample of the blood is held under low oxygen concentration, the red cells take on the sickle shape. A young woman about to be married is concerned about her future children because her brother died of sickle-cell anemia. A sample of her blood sickles under low oxygen concentration, but that red blood of her perspective husband remains normal. What can you say about the woman and the man, and about their future children? HINT: Use Punnett square to help you and receive full creditIn humans, there is a gene called sickle-cell anemia, which produces severe anemia when homozygous recessive. The name of the disease comes from the fact that many red blood cells take on abnormal sickle shape. People homozygous recessive for this trait usually die before adulthood. Heterozygous people appear normal, but when a sample of the blood is held under low oxygen concentration, the red cells take on the sickle shape. A young woman about to be married is concerned about her future children because her brother died of sickle-cell anemia. A sample of her blood sickles under low oxygen concentration, but that red blood of her perspective husband remains normal. What can you say about the woman and the man, and about their future children?
- Physical maps are maps of locations of identifiable landmarks on a genomic DNA _______ inheritance patterns.a) remotely related tob) related toc) regardless ofd) associated withAfter the rediscovery of Mendel’s principles of inheritance in the earlytwentieth century, eugenics became popular in many countries,including the United States. The eugenic movement proposed toimprove the human species through the application of genetics. Anumber of eugenic laws were passed, prohibiting the marriage ofpeople with certain conditions and allowing for the involuntarysterilization of others. Eventually this practice fell into disfavorbecause of ethical concerns and because many of the laws were basedon bad science. Some people think that the increasing use of moderngenetic techniques to test for genetic diseases and traits and tomanipulate reproductive outcomes representsthe resurgence of eugenics. What are some ethical concerns associatedwith encouraging the birth of people with desirable traits anddiscouraging the birth of those with undesirable traits?Gregor Johann Mendel carried out experiments with pea plants that demonstrated how certain physical traits were passed down from one generation to the next in a predictable pattern. He introduced the concepts of dominant and recessive traits and established fundamental laws of inheritance for what is known as Mendelian Genetics. A trait can be inherited when each parent passes down one copy of a gene. Different versions of the same gene are known as alleles. Both gene copies are an organism’s genotype, and the physical expression of those genes is a phenotype. 1. Explain one of the three laws of inheritance proposed by Mendelian genetics. Mendelian inheritance can be visualized using Punnett squares. The first row and column represent the parental alleles, while the squares predict the possible combination of alleles of the resulting offspring. Dominant alleles are indicated by uppercase letters while recessive alleles are indicated by lowercase letters. The combination of alleles in…