What is the mode of inheritance for the followingpedigree? Drag the correct answer to therectangle in the imageT=IIEIIIIV112 3223Figure 3.7 Human Molecular Genetics, 4ed. (© Garland Science)413Autosomal DominantX-linked Dominant245 658T4MitochondrialY-linkedX-linked Recessive69710

Using pedigrees, one may determine how a given trait is passed down through a family.

What is the mode of pedigree? Drag the correct answer to the rectangle in the image T = E IV 1 2 3 2 1 2 3 Figure 3.7 Human Molecular Genetics, 4ed. (© Garland Science) 4 inheritance for the following 1 3 Autosomal Dominant X-linked Dominant 5 6 5 4 X-linked Recessive Mitochondrial Y-linked 8 6 9 7 10

What is the mode of pedigree? Drag the correct answer to the rectangle in the image T = E IV 1 2 3 2 1 2 3 Figure 3.7 Human Molecular Genetics, 4ed. (© Garland Science) 4 inheritance for the following 1 3 Autosomal Dominant X-linked Dominant 5 6 5 4 X-linked Recessive Mitochondrial Y-linked 8 6 9 7 10

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter16: Human Genetics And The Human Genome

Section: Chapter Questions

Problem 11TYU

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The Online Mendelian Inheritancein Man (OMIM) databaseis a catalog of human genesand human disorders that are inheritedin a Mendelian manner. Genetic disordersthat arise from major chromosomalaberrations, such as monosomyor trisomy(the loss of a chromosome orthe presence of a superfluous chromosome,respectively), are not included.The OMIM database, updated daily, is aversion of the book Mendelian Inheritancein Man, conceived and edited by Dr. VictorMcKusick of Johns Hopkins University,until he passed in 2008.The OMIM entries provide links to awealth of information, including DNAand protein sequences, chromosomalmaps, disease descriptions, and relevantscientific publications. In this exercise,you will explore OMIM to answer questionsabout the recessive human diseasesickle-cell anemia and other Mendelianinherited disorders.Exercise I – Sickle-Cell AnemiaIn this chapter, you were introduced torecessive and dominant human traits.You will now discover more about sicklecellanemia as an…
Two mothers give birth to sons at the same time at a busy urbanhospital. The son of mother 1 has hemophilia, a disease causedby an X-linked recessive allele. Neither parent has the disease.Mother 2 has a son without hemophilia, despite the fact thatthe father has hemophilia. Several years later, couple 1 suesthe hospital, claiming that these two newborns were swappedin the nursery following their birth. As a genetic counselor, youare called to testify. What information can you provide the juryconcerning the allegation?
A young couple went to see a genetic counselor because each had a sibling with cystic fibrosis. (Cysticfibrosis is a recessive disease, and neither member ofthe couple nor any of their four parents is affected.)a. What is the probability that the female of thiscouple is a carrier?b. What are the chances that their child will havecystic fibrosis?c. What is the probability that their child will be acarrier of the cystic fibrosis disease allele?
Huntington disease is a rare dominant condition in humans that results in a slow but inexorable deteriorationof the nervous system. The disease shows what mightbe called age-dependent penetrance, which is to saythat the probability that a person with the Huntingtongenotype will express the phenotype varies with age.Assume that 50% of those inheriting the HD allele willexpress the symptoms by age 40. Susan is a 35-yearold woman whose father has Huntington disease. Shecurrently shows no symptoms. What is the probabilitythat Susan will show symptoms in five years?
Suppose two parents, a father with the genotype AaBbccDd and a mother with the genotype aaBbCcDd, want to have children. Assume the loci are inherited independently of each other. Enter your answers as the most simplified fractions (e.g. 1/8 instead of 2/16). What proportion of the offspring are expected to have: The same genotype as the father? The same phenotype as the father? All dominant phenotypes? All recessive phenotypes?
Assume that blood type is inherited as A and B dominant over O, but A and B are codominantover each other. Genotypes (IA IA) and (IA i) are then phenotypically type A, genotypes (IB IB) and(IB i) are type B, genotype (IA IB) is type AB, and genotype (i i) is type O blood. A man with bloodtype IA IA marries a woman with type AB blood. What are the genotypic and phenotypic ratios ofthe children?
In individuals affected by cystic fibrosis, salt crystals may appear afterperspiration dries up. In addition, the disease causes respiratory disorderswhich can be both debilitating and lethal. It occurs in individuals homozygousfor recessive gene. If 2 normal parents had a daughter with the symptoms ofthis disease, and a normal son, what is the probability that he might be acarrier of the recessive gene?Express answer in fraction form.
When many families were tested for the ability to tastethe chemical phenylthiocarbamide, the matings weregrouped into three types and the progeny were totaled,with the results shown below:ChildrenNumber NonParents of families Tasters tastersTaster × taster 425 929 130Taster × nontaster 289 483 278Nontaster × nontaster 86 5 218With the assumption that PTC tasting is dominant (P)and nontasting is recessive (p), how can the progenyratios in each of the three types of mating be accountedfor?
Write the genotype for each person based on : -Homozygous for B allele -Heterozygous for A allele -Type O -Type A and had a type O parent -Type AB -Blood that can be donated to anybody -Can only received blood from a type O donor There is a couple, the blood type of a male is A+ and the female is o+. What are all the possible blood types of their children in the future? Illustrate the inheritance in a Punnett Square showing all the possible blood types from the offspring of the male and female.
Epilepsy is a central nervous system (neurological) disorder in which brain activity becomes abnormal, causing seizures or periods of unusual behavior, sensations and sometimes loss of awareness. For epilepsy, the concordance values are 72% for monozygotic twins and 15% for dizygotic twins. 1) Is this a single gene inheritance or multifactorial disease? 2) Is there a strong genetic or environmental cause to the development of this disease? If both genetic and environmental causes are implicated, you have to indicate each of them separately.
Labrador retrievers may be black, brown, or golden in color (seethe chapter opening photograph on p. 53). Although each colormay breed true, many different outcomes occur if numerous littersare examined from a variety of matings, where the parentsare not necessarily true-breeding. The following results showsome of the possibilities. Propose a mode of inheritance that isconsistent with these data, and indicate the corresponding genotypesof the parents in each mating. Indicate as well the genotypesof dogs that breed true for each color.(a) black * brown ¡ all black(b) black * brown ¡ 1/2 black1/2 brown(c) black * brown ¡ 3/4 black1/4 golden(d) black * golden ¡ all black(e) black * golden ¡ 4/8 golden3/8 black1/8 brown(f) black * golden ¡ 2/4 golden1/4 black1/4 brown(g) brown * brown ¡ 3/4 brown1/4 golden(h) black * black ¡ 9/16 black4/16 golden3/16 brown
5) Humans who have an abnormally high level of cholesterol are said to suffer from familialhypercholesterolemia.  The gene for this disorder is dominant (C). A man who isheterozygous for familial hypercholesterolemia marries a woman who is homozygousfor the recessive allele. What is the probability that they will have children that sufferfrom this disorder? please draw the puutnet square and also write the parents and gemtaics top the puutnet square thanks