What response best explains why the following molecule cannot be synthesized using the malonic ester synthesis? HO O All three substituents at the alpha carbon must identical. O Acid catalyzed ester hydrolysis cannot occur in a sterically hindered molecule. O Decarboxylation reactions cannot occurin a sterically hindered molecule. O Only two substiuents can be added to the alpha carbon.

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter24: Amines And Heterocycles
Section24.9: Heterocyclic Amines
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What response best explains why the following molecule cannot be synthesized using the malonic ester synthesis?
HO
O All three substituents at the alpha carbon must
identical.
O Acid catalyzed ester hydrolysis cannot occur in a sterically hindered molecule.
O Decarboxylation reactions cannot occurin a sterically hindered molecule.
O Only two substiuents can be added to the alpha carbon.
Transcribed Image Text:What response best explains why the following molecule cannot be synthesized using the malonic ester synthesis? HO O All three substituents at the alpha carbon must identical. O Acid catalyzed ester hydrolysis cannot occur in a sterically hindered molecule. O Decarboxylation reactions cannot occurin a sterically hindered molecule. O Only two substiuents can be added to the alpha carbon.
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