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- An endoskeleton consists of _________. a. a fluid in an internal space b. hardened plat at the surface of a body c. internal hard parts d. a fluid that surrounds the bodyEach level of biological organization has emergent properties that arise from the interaction of its component parts. For example, cells have a capacity for inheritance that molecules making up the cell do not. What are some emergent properties of specific types of tissues?Cultured Skin for Healing Wounds Diabetes is a disorder in which the blood sugar level is not properly controlled. Among other effects, it reduces blood flow to the lower legs and feet. As a result, about 3 million diabetes patients have ulcers (open wounds that do not heal) on their feet. Each year, about 80,000 require amputations. Several companies provide cultured cell products designed to promote the healing of diabetic foot ulcers. FIGURE 31.15 shows the results of a clinical experiment that tested the effect of one such cultured skin product versus standard treatment for diabetic foot wounds. Patients were randomly assigned to either the experimental treatment group or the control group, and their progress was monitored for 12 weeks. FIGURE 31.15 Treatment of diabetic food ulcers. Results of a multicenter study of the effects of standard treatment versus use of a cultured cell product for diabetic foot ulcers. Bars show the percentage of foot ulcers that had completely healed. What percentage of wounds had healed at 8 weeks when treated the standard way? When treated with cultured skin?
- Effects of Kartagener Syndrome An abnormal form of the motor protein dynein causes Kartagener .syndrome, a genetic disorder characterized by chronic sinus and lung infections. Biofilms form in the thick mucus that collects in the airways, and the resulting bacterial activities and inflammation damage tissues. Men affected by Kartagener syndrome can produce sperm (FIGURE 4.20) but are typically infertile; some of them have become fathers after their sperm cells were injected directly into eggs. Review Figure 4.19, then explain these observations. FIGURE 4.20 An effect of Kartagener syndrome. Cross-section of a sperm flagellum an affected man (left) and an unaffected man (right).The smallest independently functioning unit of anorganism is a(n) ________.a. cellb. moleculec. organd. tissueThe is the basic unit of life organism cell tissue organ
- The cell of a............... Organism must carry around all of it's life function an organism made up of more that one cell is called...................... OrganismA plasma membrane ________. a. controls exchanges between the cell and the external environment b. is a mesh of intermediate filaments c. is a type of extracellular matrixSustainable Use of Horseshoe Crabs Horseshoe crab blood clots immediately upon exposure to bacterial toxins, so it can be used to test injectable drugs for the presence of dangerous bacteria. To keep horseshoe crab populations stable, blood is extracted from captured animals, which are then returned to the wild. Concerns about the survival of animals after bleeding led researchers to do an experiment. They compared survival of animals captured and maintained in a tank with that of animals captured, bled, and kept in a similar tank. FIGURE 24.28 shows the results. FIGURE 24.28 Mortality of young male horseshoe crabs kept in tanks during the 2 weeks after their capture. Half the animals were bled on the day of their capture. Control animals were handled, but not bled. This procedure was repeated 8 times with different sets of horseshoe crabs. In which trial did the most control crabs die? In which did the most bled crabs die?
- Testing Biological Control Biological control agents are used to battle red imported fire ants. Researchers have enlisted the help of Thelohania solenopsae, a natural enemy of the ants. This microsporidian (Section 23.4) is a parasite that infects ants and shrinks the ovaries of the colony's egg-producing female (the queen). As a result, a colony dwindles in numbers. Are these biological controls useful against imported fire ants? To find out, USDA scientists treated infested areas with either traditional pesticides or pesticides plus biological controls (both flies and the parasite). The scientists left some plots untreated as controls. FIGURE 45.16 shows the results. FIGURE 45.16 A comparison of two methods of controlling red imported fire ants. The graph shows the numbers of red imported fire ants over a 28-month period. Orange triangles represent untreated control plots. Green circles are plots treated with pesticides alone. Black squares are plots treated with pesticide and biological control agents (parasitoid flies and a microsporidian parasite). How did population size in the control plots change during the first four months of the study?Bacteriophage-Inspired Antibiotics Although bacteriophages have been infecting bacteria for billions of years, no mechanism, has evolved in bacteria to prevent the viruses from lysing the cell walls of their hosts. Now, scientists are targeting the same bacterial wall components that bacteriophages do. The goal is to develop antibiotics that bacteria will be less likely to develop resistance to. FIGURE 20.22 shows the results of a study to test Epimerox, a new bacteriophage-inspired antibiotic, against Bacillus anthracis, the bacterial species that causes the disease anthrax. FIGURE 20.22 Effect of Epimerox on the survival of mice with anthrax. Mice were infected with the bacteria B. anthracis. One group of 15 then began receiving a drug-free buffer solution 3 hours later. Another 15 were treated with Epimerox beginning 3 hours after infection. A third group of 15was treated with Epimerox beginning 24 hours after infection. In studies with Bacillus anthracis cells grown in culture, no Epimerox-resistant cells were observed. Explain why this result is consistent with the scientists' goal for developing this drug.Bacteriophage-Inspired Antibiotics Although bacteriophages have been infecting bacteria for billions of years, no mechanism, has evolved in bacteria to prevent the viruses from lysing the cell walls of their hosts. Now, scientists are targeting the same bacterial wall components that bacteriophages do. The goal is to develop antibiotics that bacteria will be less likely to develop resistance to. FIGURE 20.22 shows the results of a study to test Epimerox, a new bacteriophage-inspired antibiotic, against Bacillus anthracis, the bacterial species that causes the disease anthrax. FIGURE 20.22 Effect of Epimerox on the survival of mice with anthrax. Mice were infected with the bacteria B. anthracis. One group of 15 then began receiving a drug-free buffer solution 3 hours later. Another 15 were treated with Epimerox beginning 3 hours after infection. A third group of 15was treated with Epimerox beginning 24 hours after infection. What do these data indicate regarding the optimal time to begin Epimerox treatment?