What type of epigenetic changes are associated with cancer?

Q: Q7

A: Epigenetic changes include all except Change in DNA sequence. Epigenetic changes are modification in…

Q: How can the role of epigenetics in cancer be reconciled with the idea that cancer is caused by the…

A: Epigenetics is the study of various alterations in an organism occurred because of certain gene…

Q: Explain how p53 functions as a tumor suppressor gene. How can mutations in p53 lead to cancer, and…

A: Normal cell has low level of p53 protein. When DNA damage or other stress signals may trigger p53…

Q: Is the presence of oncogenic Ras necessary for transient inflammatory stimulation to induce chronic…

A: Cancer is disease in which there is uncontrolled proliferation of cell.  In organisms, cell…

Q: A normally functioning gene that regulates the cell cycle by stopping cell division is most likely…

A: Question - A normally functioning gene that regulates the cell cycle by stopping cell division is…

Q: why EGFR play a role in CRC and other cancer?

A: EGFR : It is epidermis growth factor receptor.  CRC:  Colorectal cancer. EGFR : It is one of the…

Q: Do different genes affect epigenetics and variations in epigenetic patterns between individuals?

A: Genes patterns

Q: Which are the many steps that can occur at Regulation of Gene Expression?

A: Introduction Expression of gene is highly regulated in both prokaryotes as well as in Eukaryotes. If…

Q: Which genetic cancer predisposition syndrome is caused by germ-line mutations in the p53 gene and is…

A: P53 is the tumor suppressor protein (TP53 in humans) which is also described as the guardian of the…

Q: Where Transcriptionally active genes are located ?

A: Genes are the basis of heredity. They are transferred from the preceding generation to the…

Q: What are the causes affecting by regulation of gene expression?

A: The regulation of genetic expression is likely to influence the phenotypic expression. The…

Q: Explain how Epigenetics are related with Cancer ?

A: Answer- Epigenetics is the change in the gene expression without changing the sequence of the DNA.

Q: Mutations that inactivate p53 have a recessive phenotype, whereas mutations affecting Ras are…

A: P53 is a tumor protein, which codes for the protein that regulates the cell cycle and suppresses…

Q: Explain the role of epigenetic alterations in cancer ?

A: Genes are the hereditary unit in an organism and are passed on from the parental generation to the…

Q: What is epigenetics and what are the three major epigenetic modification mechanisms?​

A: Epigenetics is the investigation of heritable changes in gene expression which don't include changes…

Q: What are the main epigenetics mechanisms

A: Epigenetics is branch of science which determine how gene expression is reshaped without changing…

Q: How can oncogenes lead to cancer?

A: Oncogenesis is a complex, multifactorial process by which normal cells turn into malignant cells.…

Q: How does methylation affect development in terms of epigenetics, cancer, and general development?

A: Methylation of DNA causes gene silencing means expression is suppressed. Methylation is associated…

Q: Describe epigenetic alterations .

A: Epigenetic is defined as the study of heritable chemical Modification of DNA or chromatin that does…

Q: What types of histone modifications are responsible for epigenetic phenotypes?

A: Histones are the set of positively charged proteins. Histones are responsible for providing…

Q: What are the three kinds of epigenetic mechanisms?

A: Epigenetic mechanisms form a layer of control within a cell that regulates gene expression and…

Q: How mutations, chromosomal changes epigenetics, and environmental agents play roles in the…

A: Cancer cells breaks the most basic rule of cell behavior by which multicellular organism are built…

Q: What protein does the P53 code for and why is it important?

A: Answer :- The TP53 quality gives guidelines to making a protein called growth protein p53 (or p53).…

Q: What is a CpG island? Where would you expect one to be located? How does the methylation of CpG…

A: A gene is a stretch of nucleotides present in the DNA. DNA or deoxyribonucleic acid is a polymer of…

Q: whose expression is affected by regulatory mutations?

A: Mutation-These are sudden changes in the gene expression which can alter the expression of…

Q: What is meant by epigenesis? How did Kaspar Friedrich Wolff ’s concept of epigenesis differ from the…

A: Epigenesis is the development of an animal or plants from the egg or spore via the processes in…

Q: Mutations in proto-oncogenes that turn them into oncogenes tend to be dominant, while cancer-causing…

A: Tumor suppressor genes are the genes that suppress the formation of tumors in the cells or tissues…

Q: Describe the underlying causes of epigenetic changes associated with cancer.

A: DNA is the genetic material in most living organisms. It is the information hub of the cell that…

Q: Which type of mutation would NOT be involved in the inactivation of a tumor suppressor gene?

A: Normal cell growth in body is controlled by -  1. Protooncogene or cellular oncogene - Protooncogene…

Q: How oncogenes contribute to cancer?

A: Cancer:       It is a disease where cells divide abnormally and damage other cells. There are…

Q: Let’s suppose you were interested in developing drugs to preventepigenetic changes that may…

A: Genes are basic physical and functional unit of heredity. It is a part of DNA that has instruction…

Q: How does an epigenetic change differ from a mutation?

A: Genetics is the study of genes, their interactions, and the effect of environment on genes. Broadly…

Q: How are tissue-specific transcription factors regulated? Identify three different ways

A: Transcription factors are the type of proteins that bind to the specific sites in the DNA and…

Q: What are enhancers and How do enhancers work?

A: Transcription is defined as the transcribing the DNA sequence into  RNA sequence by using the DNA as…

Q: How does the normal p53 protein inhibit cancer development?

A: Tumor-suppressor genes code for proteins that repair damaged DNA (preventing a cell from turning…

Q: Explain DNA methylation. How does this process influence cellular function?

A: DNA methylation is a process in which Dna bases are Methylated with the help of enzyme Methyl…

Q: eritable effects of gene expression that are not caused by a change in DNA sequence are called…

A: EPIGENETIC CHANGES are heritable changes in gene expression that do not involve changes to the…

Q: Define Epigenetic changes.  Are epigenetic changes the same thing as mutations?  Explain why or why…

A: MUTATION It is a change in a DNA sequence. Mutations can result from DNA copying mistakes made…

Q: Why does a single mutation in a proto-oncogene, turning it into an oncogene potentially lead to a…

A: Proto- oncogene Activation of a proto- oncogene into an oncogene usually includes gain of function…

Q: If a particular proto-oncogene has been altered by mutation into an oncogene such that it is…

A: Proto oncogenes are the genes which are inactivated in normal cell but when they get activated, it…

Q: Why do mutations in genes that encode DNA-repair enzymes often produce a predisposition to cancer?

A: Cancer is the disease caused by loss of control over the process of cell division.

Q: In DNA repair, how does the normal allele of BRCA1 work? Is it an oncogene or a tumor suppressor…

A: During the replication process, the base airs are mismatched or some of the base pairs undergo…

Q: How can mutations in noncoding segments of DNA contribute to the development of cancers?

A: The functions segment of hereditary material that mainly codes for the proteins is a gene. The…

Q: What makes X inactivation an epigenetic phenotype?

A: In humans, there are 23 pairs of chromosomes in which the 23rd pair is the sex chromosome which…

Q: What is haploinsufficiency? How might it affect cancer risk?

A: The term in genetics that explains the function of the dominant gene in the representation of…