What TWO strategies could be used for the development of substrate-based inhibitors for HIV aspartyl protease?

Q: Arginine and lysine side chains fit into trypsin’s binding pocket (Figure 22.5). One of these side…

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Q: Why are certain drugs called enzyme inhibitors?

A: Enzyme analysis is an important tool for medical diagnosis. It measures the activity of an enzyme…

Q: collect cholesterol from the body tissues HDL LDL VLDL Cholesterol This is a required question…

A: The correct answer is given below

Q: It decide whether act as a medicine or as a poison is: Select one: O a. Drugs O b. Selective…

A: option C dose level decides whether the medicine is medicine or poison lets take an example All the…

Q: Describe materials that serve as antigens fall into chemical categories.

A: The molecules that initiate the production of an antibody to cause an immune response is called an…

Q: Why are irreversible inhibitors considered to be poisons?

A: Solution :       Enzyme inhibitors are those molecules that interact with the enzyme to prevent the…

Q: Please solve the attached

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Q: What is the difference between tumor suppressors and oncogenes?

A: Difference between tumor suppressor and oncogene

Q: Define the optimum pH for enzyme activity.

A: The optimum pH for enzyme activity is defines as follows:

Q: What are the various types of hepatitis? Discuss the cause, transmission, occurrence, alternate…

A: A question based on introduction to Chemistry that is to be accomplished.

Q: affected

A: The structure of the SARS-CoV2 virus contains different type of proteins and these are Envelope ,…

Q: Selective COX-2 inhibitors are preferable than nonselective COX- inhibitors. How can selective COX-2…

A: COX- inhibitors are a type of non-steroidal inhibitors that directly targets cyclooxygenase- 2.  It…

Q: Which pathogens/diseases activate humoral immunity? Describe the mechanism of this activation.

A: Pathogens  It is a organism which cause disease . They are four type of pathogens Fungi Bacteria…

Q: SUBSTRATE Is this an example of competitive or nonçompetitive inhibition? substrate SUBSTRATE shes…

A: The chemical or biological compound which can alter the rate of a reaction and can be restored at…

Q: Explain why patients with AIDS have deficiencies in antibody formation.

A: AIDS is caused by HIV (Human Immunodeficiency Virus).

Q: What is true about an irreversible noncompetitive inhibitor? it forms a covalent bond to the enzyme…

A: In normal situations, non competative inhibitors are reversible. Sometimes they are not influenced…

Q: What is the mechanism of action of the antibiotic drug Sulfanilamide in terms of enzyme inhibition?

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Q: Which of the following enzymatic biomarkers is/are correctly paired? Cardiac injury: Troponin I…

A: Cardiac isoforms of troponin are specific for heart. Increased troponin level indicates cardiac…

Q: < This cartoon depicts which type of enzyme inhibition? R Question 14 of 15 Substrate Inhibitor…

A: #Q.1: #A: In competitive inhibition, the inhibitor binds at the site where the substrate is attached…

Q: The vast majority of serine protease inhibitors are competitive inhibitors. Which of the following…

A: Given statements, The Vmax of a reaction decreases in the presence of a competitive inhibitor. Km…

Q: Suppose a mutation in an enzyme resulted in the replacement of a leucine with a serine in the active…

A: The protein molecules that act as catalysts in the metabolic reactions and speed up the metabolic…

Q: Two cystine amino acids hold together two separate beta sheets. This is an example of side chain…

A: There are various types of interactions present in proteins-  1- hydrophobic interaction 2-…

Q: 1. What is the role of initiator and inhibitor? 2. What are short stops?

A: Since you have posted multiple questions, we will answer only first question for you. If you want…

Q: When designing a competitive inhibitor, why might the substrate, transition state, and product of an…

A: Answer -  competitive inhibitor - According to the question - In competitive inhibition, an…

Q: hoose the amino acid most likely to serve as a proton donor in the active site of an enzyme:…

A: ANSWERE IS :

Q: Explain about ciguatoxin CTX3C, ?

A: Ciguatoxina are  toxic polycyclic polyethers seen in sea fish . CTX is used as an abbreviation to…

Q: A narrow spectrum antibiotic is active against _______________. (i) gram positive or gram negative…

A: Given,A narrow spectrum antibiotic is active against _______________.(i) gram positive or gram…

Q: What most correctly describes the relationship between pathogens and antigens?    1. Our own body's…

A: When the presence of antigen inside the body is detected, body’s own cell attacks on that antigen…

Q: The factors that denature enzyme activity are temperature, pH, salinity, alcohol and surface area.…

A: Effect of temperature: Velocity of an enzyme reaction increases with increase in temperature up to a…

Q: Which of the following scenarios DOES NOT point to the procurement of an assay? A. a certain type of…

A: An assay includes an analytical procedure through which a sample is checked qualitatively or…

Q: Briefly explain the difference between competitive and noncompetitive inhibitors.

A: Applying concept of inhibition of enzyme inhibitors based on their binding sites.

Q: Which inhibitor does the statement describe: 1. The structure of the inhibitor is similar to that of…

A: 1) Given: The structure of the inhibitor is similar to that of the substrate.

Q: What are the primary modes of transmission of the coronavirus? sneezing b. metal surfaces c.…

A: COVID-19 virus is primarily transmitted between people through respiratory droplets and contact…

Q: Human Immunodeficiency Virus belongs to the family: A.Retroviridae B.Retroviridians C.Retroviral…

A: Human Immunodeficiency Virus belongs to the family Retroviridae.

Q: Describe how the following function as drugs: (a) AZT  (b) cisplatin  (c) daunomycin

A: (a) AZT: Anti-viral (b) cisplatin: Anti-cancer (c) daunomycin: Anti-viral

Q: Is the inhibitor competitive, uncompetitive or non competitive and why?

A: Competative inhibiton- The inhibitor Binds only free enzyme. Binding occur only free enzyme. Non…

Q: What is the process that involves the breaking of intermolecular forces that hold an enzyme into the…

A: Enzymes are bio-catalysts that speed up the biochemical reactions occurring in the living system.…

Q: Which of the following cell types is NOT part of the innate immune system? a.monocytes b.lymphocytes…

A: A living body encounters with many harmful disease which occur due to different called…

Q: Which type of an enzyme inhibition can be affected by the substrate concentration?     a.…

A: Uncompetitive inhibition and competitive inhibition can be effected by substrate concentration.

Q: Make the best matches to the following three terms. noncompetitive inhibitor inhibitor competitive…

A: The biochemical reactions are catalyzed by some catalyst which are known as enzymes.

Q: If the vaccine effectiveness towards providing protection from hospitalization is 90% which of the…

A: The statement is dealing with only vaccinated people so we can ignore the options related to…

Q: Classify each specific inhibitor or inhibitor characteristic according to one of two types of…

A: The solution is given below -