What would be the effect of the inhibition on other intermediates in the citric acid cycle?

Q: Explain what will happen to reactions of pyruvate dehydrogenase complex when there is a deficiency…

A: Pyruvate dehydrogenase complex (PDC) is a complex formed by 3 enzymes that converts pyruvate into…

Q: What is the main purpose of the citric acid cycle?

A: The citric acid cycle is also called a tricarboxylic cycle where oxidation of fuel such as…

Q: Describe the citric acid cycle. In how many steps does it take place? What is the substrate? What…

A: The citric acid cycle is also recognized as the TCA (tricarboxylic acid) cycle or the Krebs cycle.…

Q: Which of the following cofactors is NOT used by the pyruvate dehydrogenase complex? a. NAD+ b. FAD…

A: The pyruvate formed by the process of glycolysis is converted into acetyl-CoA. The reaction is…

Q: Why does it make metabolic sense for ADP and GDP to inhibit ribose phosphate pyrophosphokinase?

A: Ribose phosphate phosphokinase or ribose-phosphate pyrophosphokinase (RPPK) is a phosphoribosyl…

Q: Which one of the five steps of the pyruvate dehydrogenase complex reaction is most likely to be…

A: Pyruvate dehydrogenase complex is a group of non-covalently associated enzymes. It catalyzes…

Q: Why, do you suppose, the coenzyme for the reaction in the citric acid cycle that is catalyzed by…

A: Succinate dehydrogenase is an enzyme complex found in inner mitochondrial membrane and participates…

Q: The intermediates of glycolysis are phosphorylated, but those of the citric acid cycle are not.…

A: The citric acid cycle has several enzymes that are used in a chemical reaction. It is a part of…

Q: There are three steps in the Kreb cycle (beginning at pyruvate) where a single carbon is removed. In…

A: Glycolysis is the main process of cellular respiration involving glucose (6C) conversion to two…

Q: The citric acid cycle itself, which is composed of enzymatically catalyzed steps, can be thought of…

A: Citric acid cycle is also known as Krebs cycle or TCA cycle. This cycle occurs in the matrix of…

Q: How would a riboflavin deficiency affect the functioning of the citric acid cycle? Explain your…

A: The process of breakdown of glucose to generate the energy molecule adenosine triphosphate (ATP) is…

Q: What two major kinds of chemical reactions occur in the citric acid cycle, and how are these…

A: The citric acid cycle involves a series of reactions that take place in the matrix of the…

Q: How are enzymes in Citric Acid Cycle regulated? What are these enzymes and their inhibitors?

A: Cellular metabolism is the set of all reactions that are involved in producing energy in the body.…

Q: What enzymes from the citric acid cycle that are allosterically regulated by ATP and/or NADH?  What…

A: TCA cycle: - In this cycle, the activated acetate derived from pyruvate undergoes stepwise oxidation…

Q: What enzymes outside of the citric acid cycle affect itsregulation?

A: Citric acid cycle is also known as the tricarboxylic acid [TCA] cycle and Krebs cycle. The pyruvic…

Q: What step in the citric acid cycle in inhibited by fluorocitrate?

A: The citric acid cycle is a series of chemical reactions used by all aerobic organisms to release…

Q: What would be the effect on fatty acid synthesis of a mutation in ATPcitrate lyase that reduces the…

A: Biomolecules are organic molecules that occur and function in living systems. Biomolecules consist…

Q: What is the function of NAD+ in the pyruvate dehydrogenase complex?

A: Pyruvate is formed from glycolysis. This pyruvate gets converted to acetyl CoA by oxidative…

Q: The pyruvate →lactate reaction in animals is reversible, but the pyruvate → ethanol fermentation in…

A: Anaerobic respiration or fermentation is conversion of glucose into energy which is very less as…

Q: What are the two most common inhibitors of stepsof the citric acid cycle and the reaction catalyzed…

A: The citric acid cycle that takes place in the mitochondrial matrix is the second step of aerobic…

Q: What electron acceptors play a role in the citric acid cycle?

A: Citric acid cycle:          The Citric acid cycle also described as TCA cycle or the krebs cycle, in…

Q: How many moles of ATP are synthesized by adding stearate to TCA through B-oxidation? Why is that?…

A: From the Beta oxidation process: The P/O ratios, which give the number of ATP produced per molecule,…

Q: A  drug inhibits the activity of the enzymatic inorganic pyrophosphatase. What effect would the drug…

A: DNA synthesis is the process whereby deoxynucleic acids (adenine, thymine, cytosine, and guanine)…

Q: Which reaction in the citric acid cycle is most analogous to the oxidative decarboxylation of 6-…

A: Oxidative decarboxylation is a process of removal of carbon group by oxidation reaction which…

Q: Discuss the assertion that the Citric acid cycle is central for metabolism.

A: The citric acid cycle involves a series of chemical reactions to release stored energy through the…

Q: Identify the primary catabolic purpose of the citric acid cycle

A: The citric acid (CAC) cycle is the primary catabolic process, which helps to convert the pyruvate…

Q: What are the similarities and differences between the reactions catalyzed by pyruvate dehydrogenase…

A: Introduction Respiration is a metabolic process involving the oxidation of organic compounds to form…

Q: Why is the citric acid cycle the most efficient way to oxidise Acetyl CoA?

A: The citric acid cycle (CAC), also known as the TCA cycle (tricarboxylic acid cycle) or the Krebs…

Q: Why is the TCA cycle is important for both anabolic and catabolic reactions?

A: After each turn of the TCA cycle, oxaloacetate is regenerated and can combine with another…

Q: Malonate is a competitive inhibitor of succinate dehydrogenase. How will the concentrations of…

A: The citric acid cycle is inhibited by the high concentration of ATP,acetyl-CoA, and NADH which…

Q: What are the two unique enzymes of glyoxylate cycle and their reactions? What main role of the cycle…

A: The main purpose of the glyoxylate cycle is the use of acetyl-CoA for the production of glucogenic…

Q: Which reactions of the citric acid cycle transfer energy as FADH2?

A: FAD acts as coenzyme which accepts the electrons and protons get reduced to FADH2.

Q: Why is the enzyme-catalyzed introduction of carbon–carbon double bonds into fatty acids called an…

A: Beta-oxidation is a metabolic process by which fatty acids are broken to acetyl-CoA. It occurs by…

Q: What is the reaction catalyzed by glucose 6-phosphatase?

A: Glucose 6-phosphate : It is a glucose sugar phosphorylated at the hydroxy group on carbon 6.

Q: How many NADH and how many FADH2 molecules are formed in the citric acid cycle?

A: Citric acid cycle : It is a series of chemical reactions used by all aerobic organisms to release…

Q: How is it possible for fluoroacetate to enter the citric acid cycle?

A: Carbohydrates, in particular glucose, is preferred biomolecule for ATP generation. Glucose is…

Q: Question attached

A: The Citric (CAC) acid cycle is the process, which helps to produce oxalo (OAA) acetate with the…

Q: Explain the reasons for the oxidation of acetate through complex pathways in the citrate cycle.

A: TCA or tricarboxylic acid cycle is the second step of aerobic cellular respiration. It is an…

Q: What substance acts as the starting point of the citric acid cycle, reacting with acetyl-CoA in the…

A: Acetyl CoA : It is a molecule that participates in many biochemical reactions in protein,…

Q: What citric acid cycle intermediate would be regenerated?

A: A sequence of metabolic pathways takes place in the process of cellular respiration to transform…

Q: What citric acid cycle intermediates are precursors to amino acids?

A: Cellular respiration is the process in which cells consume oxygen and produces carbon…

Q: An intermediate of the citric acid cycle that undergoes reductive amination with glutamine as…

A: The citric acid cycle is a set of chemical reactions that release energy from carbs, lipids, and…

Q: What are the substrates and products of the net reaction corresponding to one turn of the citric…

A: Introduction: The TCA cycle fundamentally includes the association of a two-carbon acetyl CoA with…

Q: Why is the citric acid cycle a cycle?

A: The citric acid cycle is a part of the cellular respiration process where acetyl CoA is involved in…

Q: What is the purpose of the citric acid cycle?

A: The citric acid cycle is also know as the Krebs cycle or tricarboxylic acid cycle which is a centre…

Q: What is the purpose of converting citrate to isocitrate in the Citric Acid Cycle?

A: Krebs cycle is also known as the citric acid cycle or tricarboxylic acid cycle. This cycle takes…