Why does it make metabolic sense for ADP and GDP to inhibit ribose phosphate pyrophosphokinase?

Q: Why does biological Fe2+ oxidation under oxic conditions occurmainly at acidic pH?

A: Oxic condition refers to the process or environment in which oxygen is involved.

Q: Why does it make good metabolic sense for phosphoenolpyruvate carbox- ykinase, rather than pyruvate…

A: Phosphoenolpyruvate carboxylase is an enzyme in the family of carboxy-lyases found in plants and…

Q: How does the action of allosteric effectors differ in the reactions catalyzed by phosphofructokinase…

A: Glycolysis is breakdown of glucose. It is a ten step enzymatic process. Phosphofructokinase is an…

Q: How does control of the glucose6-phosphatase reaction differ from that of the fructose-1,6-…

A: Gluconeogenesis is the formation of glucose. It resembles reversal of glycolysis. Three steps of…

Q: What is the simplest explanation in the notion that phosphofructokinase is a regulated enzyme?

A: Phosphofructokinase regulated by ATP, an ADp derivative called AMP, and citrate, as well as some…

Q: What is the function of the kinase associated with the pyruvate dehydrogenase complex?

A: Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that converts pyruvate into…

Q: How does the inhibition of ATP-ADP translocase affect the citric acid cycle? Glycolysis?

A: Glycolysis: It is defined as the process of partial oxidation of glucose to form two molecules of…

Q: Is the statement during fatty acid biosynthesis, NADH is used as the reducing equivalent in the…

A: Ans: Fatty acid synthesis, the process formation of fatty acids from acetyl CoA and NADPH with the…

Q: Why is pyruvate carboxylase constitutive and active in both glycolysis and gluconeogenesis?

A: The pyruvate carboxylase got multiple sub units of enzymes. Here acetyl CoA helps as an regulatory…

Q: How many protons are shuttled from the matrix to the intermembrane space by the products of the…

A: Reduced coenzymes NADH and FADH2 retains most of the free energy produced during the process glucose…

Q: How does control of the glucose-6-phosphatase reaction differ from that of the…

A: Glucose-6-phosphatase is an enzyme that catalyzes the hydrolysis of glucose-6-phosphate into glucose…

Q: Why is AMP and not ADP the positive regulator of phosphofructokinase?

A: Metabolic pathways are defined as the set of chemical reactions occurring in the body. Metabolic…

Q: How does the action of allosteric effectors differ in the reactions catalyzed by phosphofructokinase…

A: Allosteric effectors are the molecules that bind with one of the active sites of an enzyme that are…

Q: What is the total ATP produced from complete oxidation of 10 molecules of glucose asumming that the…

A: Glycolysis is the process in which glucose is converted into pyruvate, with the production of ATP,…

Q: What are the 3 modifications that prepare pyruvate for the Krebs Cycle?

A: Pyruvic acid (CH3COCOOH) is the simplest of the alpha-keto acids and is an organic acid and a…

Q: Why is the Krebs cycle considered part of aerobic metabolism, even though O2 does not appear in any…

A: Asked : Reason for kreb's cycle : part of aerobic metabolism

Q: Under anaerobic circumstances, why is pyruvate converted to lactate?

A: Anaerobic Glycolysis is the process of glucose oxidation that occurs when oxygen levels are low,…

Q: Considering the evidence that led Krebs to propose a cyclic pathway for oxidation of pyruvate,…

A: Introduction: Metabolically plants and animals are different in several metabolic stages. Plants…

Q: How many moles of ATP are synthesized by adding stearate to TCA through B-oxidation? Why is that?…

A: From the Beta oxidation process: The P/O ratios, which give the number of ATP produced per molecule,…

Q: Why does it make metabolic sense for UTP to inhibit carbamoyl phosphate synthetase II, whereas ATP…

A: Feedback inhibition is a cellular control mechanism in which the activity of the enzyme is inhibited…

Q: Why is the TCA cycle considered to be the central pathway in the energy metabolism of a cell?

A: The citric acid cycle serves a number of vital activities in addition to supplying energy from the…

Q: Which amino acids can be converted to pyruvate by a single enzyme-catalyzed reaction?

A: Pyruvate is a three-carbon compound that is the end product of the glycolysis pathway. Pyruvate is…

Q: What is deltaG" for this reaction ATP + glucose -> ADP + giucose-6-phosphate deltaG"= ?

A: Glycolysis: a cytoplasmic pathway in which  glucose breaks down into two three-carbon compounds and…

Q: What would be the effect of the inhibition on other intermediates in the citric acid cycle?

A: Citric acid cycle occurs in the matrix of mitochondria (cytosol in prokaryotes). The net result of…

Q: How many ATPs are synthesized for every cytoplasmic NADH reducing equivalent that is transferred…

A: The malate-aspartate shuttle is a biochemical system for translocating electrons produced during…

Q: How do the cytosolic and mitochondrial isozymes of glycerol 3-phosphate dehydrogenase differ from…

A: Glycerol-3-phosphate dehydrogenase, abbreviated as GPDH is an enzyme that is responsible for the…

Q: What are the similarities and differences between the reactions catalyzed by pyruvate dehydrogenase…

A: Introduction Respiration is a metabolic process involving the oxidation of organic compounds to form…

Q: What is the stoichiometry of the synthesis of (a) ribose 5-phosphate from glucose 6-phosphate…

A: Stoichiometry involves the relationships between the reactants and/or products in the chemical…

Q: Why is pyruvate converted to lactate under anaerobic conditions?

A: Anaerobic Glycolysis was the process of oxidation of glucose that takes place when the oxygen levels…

Q: Why must glucose be “primed” with a high-energy phosphate bond before it can be degraded in the…

A: Glucose is the most abundant monosaccharide made by plants and most algae during photosynthesis from…

Q: What is the advantage for some tumors to stop expressing the genes for glucose-6-phosphatase,…

A: Glucose-6-phosphate, phosphoenolpyruvate carboxykinase, and fructose bisphosphatase are the three…

Q: What is the advantage of activating pyruvate kinase with fructose-1,6-bisphosphate?

A: Glycolysis is the metabolic pathway that converts glucose into pyruvate and hydrogen ion through…

Q: What coenzymes are required by the pyruvate dehydrogenase complex? What are their roles?

A: A coenzyme is a non-protein component of an enzyme that is required for the enzymatic reaction to…

Q: When 13C-labeled CO2 is used in the gluconeogenesis pathway, does the resulting glucose contain 13C?…

A: Gluconeogenesis is a metabolic pathway that results in the generation of glucose from certain…

Q: What are the coenzymes of El and E2 of pyruvate dehydrogenase complex? Explain their roles and…

A: Pyruvate dehydrogenase complex is a complex of three enzymes that converts pyruvate into acetyl-CoA…

Q: Why does it make good metabolic sense for phosphoenolpyruvate carboxykinase, rather than pyruvate…

A: Guconeogenesis is the process whereby glucose is formed from non-carbohydrate metabolic substrate…

Q: How many NADH and how many FADH2 molecules are formed in the citric acid cycle?

A: Citric acid cycle : It is a series of chemical reactions used by all aerobic organisms to release…

Q: Considering the evidence that led Krebs to propose a cyclic pathway for oxidation of pyruvate,…

A: The Citric acid cycle, or the Tri-carboxylic acid cycle is commonly known as the Kreb's cycle, which…

Q: what are the components of Pyruvate dehydrogenase Enzyme complex ?

A: Pyruvate dehydrogenase Enzyme  complex is made up of three Enzymes and requires 5 coenzymes .

Q: What prevents the phosphatase activity of PP1 from always inhibiting glycogen degradation?

A: Introduction: Glycogen is stored in the liver and skeletal muscle. To maintain the glucose levels in…

Q: What is the effect of the mutation on succinate-coupled ATP synthesis?

A: Succinate : It is a dicarboxylic acid dianion resulting from the removal of a proton from both of…

Q: Does thiamine pyrophosphate play a role in the reactions of the pentose phosphate pathway? If so,…

A: Yes, thiamine pyrophosphate plays a very important role in the reaction of the pentose phosphate…

Q: If the pyruvate is labelled with 14C at its carbonyl carbon, how many rounds of the TCA cycle are…

A: Glycolysis is the primary biochemical pathway of cellular respiration that involves the conversion…

Q: When regulating phosphofructokinase, why is there such extensive regulation of this reaction and…

A: Glycolysis is a metabolic pathway that involves breaking down glucose to produce pyruvate and…

Q: Explain why rotenone inhibits oxidative phosphorylationwhen the substrate is pyruvate, but not when…

A: Site-specific inhibitors of electron transport have been identified. These compounds prevent the…

Q: explain the difference between pyruvate carrier and pyruvate dehydrogenase complex?

A: Pyruvate refers to the conjugate base of pyruvic acid is an important intermediate in many metabolic…

Q: What are the metabolic effects of not being able to produce the M subunit of phosphofructokinase?

A: Introduction: One of the most significant glycolysis regulating enzymes is phosphofructokinase-1…

Q: Does Pyruvate Dehydrogenase Complex have coenzymes and Allosteric regulation?

A: Pyruvate dehydrogenase complex (PDC) is a three-enzyme complex that decarboxylates pyruvate into…

Q: What is the metabolic advantage of having both hexokinase and glucokinase to phosphorylate glucose?

A: The enzyme kinase is a class of enzymes that are involved in the addition of the phosphate group to…

Metabolic pathways

Metabolism is defined as the group of life-supporting, enzyme-mediated chemical reactions in organisms. A metabolic pathway is a set of these chemical reactions that involve anabolism (synthesis of complex biomolecules) and catabolism (breakdown of biomolecules into small molecules) that occur inside a cell. Metabolites are the reacting substances, products, and intermediate substances of an enzymatic process that are altered by a series of chemical events catalyzed by enzymes.