When challenged with a low oxygen environment, knownas hypoxia, the body produces a hormone called erythropoietin(EPO), which then stimulates red blood cell production tocarry more oxygen. Transcription of the gene encoding EPO isdependent upon the hypoxia-inducible factor (HIF), which is atranscriptional activator. However, HIF alone is not sufficientto activate EPO. For example, Wang et al. (2010. PLOS ONE 5:e10002) showed that HIF recruits another protein called p300to an enhancer for the EPO gene. Furthermore, deletion of p300significantly impaired transcription of the EPO gene in responseto hypoxia. Given that p300 is a type of histone acetyl transferase,how might p300 influence transcription of the EPO gene?

Q: High throughput whole genome sequencing, RNA-seq and ChIP-seq have all been made possible by the adv...

A: Next gen Sequencing or NGS is one of the revolutionary technology for the DNA sequencing. This techn...

Q: What is deadenylation-independent decay? What is the role of deadenylation-independent decay ?

A: Degradation of messenger RNAs (mRNAs) plays a vital role in the modulation of expression of gene and...

Q: What is the meaning of BSC or biological safety cabinet and why is it important and how is it works?

A: Introduction: Biosafety issues refer to the procedures, policies, and principles to be adopted to sa...

Q: Instruction: Read Chapter 5. The Hemoflagellates of the book Clinical Parasitology: A Practical appr...

A: ANSWER;- ● Leishmania - Leishmania is a flagellated protozoan causing Kala Azar. These are obligate ...

Q: What are the main respective components of cell walls in bacteria, protists, fungi and plants?

A: Cell wall It is a structural layer that surrounds some types of cells,  situated outside the cell m...

Q: In humans, discoloration of the teeth is controlled by the dentine sialophosphoprotein (DSPP) gene i...

A: The normal colour of teeth is white hue color, a very slight yellowish layer for protection. 

Q: In squash soup, what are the enzymes and pigments present?

A:  squash soup is Made with squash, ginger, rosemary & sage, it's super creamy . There can be some...

Q: 14. Which if the following statements is most likely behaviorally when applied to a male primate wit...

A: There are 376–522 species of living primates, depending on which classification is used. New primate...

Q: Within the field of phylogenetics, what does a “bootstrap value” represent?

A: Introduction: Phylogeny is the study of the organisms with respect to its evolution and the relation...

Q: Define about posttranslational modifications within the proteome ?

A: A complete set of proteins expressed by an organism is called a proteome. In other words, assortment...

Q: RabA3 mi51 RabD2.a GA1 RabA5.b RabA5.e RabA2.b ZabA1.a RabE1.e rga RabC2.b RabD1 RabE1.d RNS1 MNSOD ...

A: Rab GTPase comes under the the ras superfamily of regulatory GTPase which mainly regulates the membr...

Q: The following is a synthesis sequence or progression that is a hypothesis for Chemical evolution: el...

A: Introduction :- Chemical evolution is a third theory of life's genesis. Pre-biological transformatio...

Q: What is the purpose/function of glutelins?

A: Glutelin They are a class of protein prolamin proteins found in the endosperm of certain seeds of th...

Q: 8) Describe the homeostatic mechanisms that Lacy's body would use to counteract the water deficit

A: Two kidneys are present just near the abdomen area. These are bean-shaped. They are the most essenti...

Q: tion is not graded, however, I'd like to ask for the correct answer to ease my mind and add further ...

A: Our world is full or biodiversity. All kind of life forms found on our earth refers as the biodivers...

Q: Which letter is pointing to the female Ascaris?

A: Kingdom Animalia is a vast kingdom which comprises of animals.  It is divided into vertebrates and i...

Q: What contributes to the asymmetric protein distributions ?

A: The lipid bilayer (or phospholipid bilayer) is a thin polar membrane made of two layers of lipid mol...

Q: Where is CSF usually obtained for examination and explain why.

A: Cerebrospinal fluid (CSF) is a clear, colourless bodily fluid found in the tissue that surrounds all...

Q: Mind map about brain functions left and right hemisphere.

A: Brain It is the central information processing organ of our body and act as the command and control...

Q: In cultivated flowers called “stocks,” the recessive genotype of one locus (aa) prevents the develop...

A: Given: In cultivated flowers called “stocks,” the recessive genotype of one locus (aa) prevents the ...

Q: Two sequences aligned using one of the BLAST programs produce an alignment with an expected value (E...

A: *A BLAST alignment will have an  pair of sequences in which every letter in one sequence is paired w...

Q: 31. One of the reasons that primates have been so evolutionaritly successful for the past 55 million...

A: The primate is a group (class) of mammals under sbuphylum vertebrata includes lemurs, lorises, tarsi...

Q: Does a negative change in carbon dioxide per minute indicate photosynthesis or cellular respiration

A: Carbon dioxide removal, is known as negative CO2 emissions, is a process in which carbon dioxide gas...

Q: What is the name of the DNA duplication process? What is the main enzyme that participates in it?

A: *The duplication means the doubling of DNA from one DNA. *Replication means it is the process in whi...

Q: summarize basic information with photos: Family name, scientific name, common name, hosts/damage, li...

A: The forest tent caterpillar moth is a moth found all through North America, particularly in the east...

Q: Select the correct class out of the following: Trematoda, Cestoda, Filaria, Loa, Trichinella, Necato...

A: Introduction A parasite is a creature that lives on or in its host and feeds on or at the expense of...

Q: Which of the following statements best summarizes the differences between DNA and RNA? A) DNA is tr...

A: There are two main types of genetic materials: DNA RNA

Q: Describe how the anti-retroviral drug Tenofovir prevents replication of HIV-1. Be sure to describe w...

A: Tenofovir is a nucleotide analog reverse transcriptase inhibitor which is used in the management of ...

Q: A small group of finches from the mainland United States get blown off course during a hurricane and...

A: The mechanism by which species evolve over time is known as evolution. Genetic variety in population...

Q: 4. What is the nitrogen base pair of Adenine in transcription? * Cytosine O Uracil O guanine thymine...

A: Nucleic acid is biological macromolecules that is exhibited inside the nucleus is the cell. It consi...

Q: You co-culture the following bacterial strains: an Hfr prototroph and an F- auxotroph for the genes ...

A: Introduction: HFr is a high-frequency recombination bacterial cell whose sex plasmid is attached to ...

Q: What is deadenylation- dependent decay ?

A: Basically, deadenylation stands for the removal of an adenylate group from any part of protein. All ...

Q: 1. BUILD YOUR OWN CLADOGRAM. DIRECTIONS: Given the following organisms, create a simple cladogram an...

A: Cladogram is use to construct to show the difference and similarities between different organisms du...

Q: The 5'-Cap on viral MRNA plays a critical role in: Maturation and stability of the MRNA Translocatio...

A:  In eukaryotes, the 5′ cap (cap-0), found on the 5′ end of an mRNA molecule, consists of a guanine n...

Q: High throughput whole genome sequencing, RNA-seq and ChIP-seq have all been made possible by the adv...

A: Next generation sequencing Technology:  This is a high throughput approach of DNA sequencing by whic...

Q: The immediate source of energy for DNA replication is (a) the hydrolysis of nucleotides with three p...

A: Introduction  Nucleotide: it is comprised of a pentose sugar attached to a nitrogenous base on carbo...

Q: Explain the significance why protein extraction is important

A: Introduction: Proteins are the nitrogenous organic compounds which are composed of one or more long ...

Q: IV. BIOLOGICAL CLASSIFICATION. DIRECTIONS: Determine the correct biological classification for human...

A: Biological classification is classifying or arranging an organism on the basis of the same character...

Q: What is known as Src phosphorylates ZBP1 ?

A: Introduction: The localization of beta-actin messenger RNA to the sites of active actin polymerizati...

Q: Define RNA interference (RNAi)  mechanism ?

A: RNA interference is a natural phenomenon, where an mRNA is silenced so it inhibits the protein coded...

Q: 1) you have a locus in your PCR reaction that is a DNA squence is on the fifth chromosome, is a sing...

A: Gel electrophoresis is a common laboratory method used for the separation of DNA, RNA, or proteins o...

Q: The proteasome is a multi-subunit machine that unfolds anddegrades proteins. How is its activity reg...

A: The proteasome is an exceptionally refined protease complex intended to complete particular, effecti...

Q: Blocking the ability of DNA methyltransferases to target the glucocorticoid receptor gene would like...

A: DNA methyltransferases These are a conserved family of cytosine methylases that are involved in epig...

Q: Q3: Describe how a positive autoregulatory loop works in the context of the HIV-1 Tat proteins. Be s...

A: Positive autoregulatory means transcription factor is either directly or indirectly activate its own...

Q: What chemical substances compose the plasma membrane?

A: The plasma membrane is a thin, flexible barrier that separates the interior of a cell from its envir...

Q: The 5'-Cap on viral mRNA plays a critical role in:

A: In molecular biology the 5' cap is a specially altered nucleotide on the 5' end of primary transcrip...

Q: DNA from a strain of Bacillus subtilis with genotype a+ b+ c+ d+ e+ is used to transform a strain wi...

A: Co transformation means that the two genes are transformed simultaneously. Is two genes are co trans...

Q: Briefly explain how bacteriophages can transduce genes between bacteria

A: Introduction :- Bacteriophages (BPs) are bacteria-infecting viruses that kill bacteria without harmi...

Q: What common features are shared by most cell signaling systems?

A: The key membrane-bound unit that contains the basic molecules of life and is composed of which all l...

Q: Mutations that affect organisms are those that involve exons. True or False

A: Mutation takes place when section of gene or exons are missing. The most common type of mutation tha...