In humans, discoloration of the teeth is controlled by the dentine sialophosphoprotein (DSPP) gene in chromosome 4. The allele for yellow-brown teeth color (D) is completely dominant to the allele for normal teeth (d). This condition has been found to be associated with another genetic condition, Osteogenesis imperfecta, characterized by having brittle bones. One type of this disorder occurs when two copies of the recessive allele (c) for collagen type I (COL1A1) gene are present in an individual's chromosome 17. A man with normal teeth and who exhibits a mild case of Osteogenesis imperfecta (Ol) was born to a father who has discolored teeth and a mother who has normal teeth. Both the man's father and mother do not manifest Ol. What is the genotype of... a. a.1. the man's father? a.2. the man's mother? b. If this man in (a) would marry, what should be the genotype of his wife in order that none of their future children will manifest any of the conditions? Support your answer by showing the cross.

In humans, discoloration of the teeth is controlled by the dentine sialophosphoprotein (DSPP) gene in chromosome 4. The allele for yellow-brown teeth color (D) is completely dominant to the allele for normal teeth (d). This condition has been found to be associated with another genetic condition, Osteogenesis imperfecta, characterized by having brittle bones. One type of this disorder occurs when two copies of the recessive allele (c) for collagen type I (COL1A1) gene are present in an individual's chromosome 17. A man with normal teeth and who exhibits a mild case of Osteogenesis imperfecta (Ol) was born to a father who has discolored teeth and a mother who has normal teeth. Both the man's father and mother do not manifest Ol. What is the genotype of... a. a.1. the man's father? a.2. the man's mother? b. If this man in (a) would marry, what should be the genotype of his wife in order that none of their future children will manifest any of the conditions? Support your answer by showing the cross.

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Description: In humans, discoloration of the teeth is controlled by the dentine sialophosphoprotein (DSPP) genein chromosome 4. The allele for yellow-brown teeth color (D) is completely dominant to the allele for normalteeth (d). This condition has been found to

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 16QP: Familial retinoblastoma, a rare autosomal dominant defect, arose in a large family that had no prior...

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