When DNA is heated, it denatures; that is, the strands separate because hydrogen bonds are broken and some base-stacking and hydrophobic interactions are disrupted. The higher the temperature, the larger the number of hydrogen bonds that are broken. After reviewing DNA base pair structure, determine which of the following molecules will denature first as the temperature is raised. Explain your reasoning. a. 5′-GCATTTCGGCGCGTTA-3′ 3′-CGTAAAGCCGCGCAAT-5′ b. 5′-ATTGCGCTTATATGCT-3′ 3′-TAACGCGAATATACGA-5′

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter8: The Structure, Replication, And Chromosomal Organization Of Dna
Section: Chapter Questions
Problem 12QP: DNA contains many hydrogen bonds. Are hydrogen bonds stronger or weaker than covalent bonds? What...
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When DNA is heated, it denatures; that is, the strands separate because hydrogen bonds are
broken and some base-stacking and hydrophobic interactions are disrupted. The higher the
temperature, the larger the number of hydrogen bonds that are broken. After reviewing DNA
base pair structure, determine which of the following molecules will denature first as the
temperature is raised. Explain your reasoning.
a. 5′-GCATTTCGGCGCGTTA-3′
3′-CGTAAAGCCGCGCAAT-5′
b. 5′-ATTGCGCTTATATGCT-3′
3′-TAACGCGAATATACGA-5′

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