a) In a DNA double helix, why doesn't an A or T form two hydrogen bonds (out of the three possible) with G or C? b) Why is RNA structure so unstable? c) Explain how DNA replication is bidirectional and discontinuous in nature?

a) In a DNA double helix, why doesn't an A or T form two hydrogen bonds (out of the three possible) with G or C? b) Why is RNA structure so unstable? c) Explain how DNA replication is bidirectional and discontinuous in nature?

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter11: Genome Alterations: Mutation And Epigenetics

Section: Chapter Questions

Problem 18QP: Replication involves a period of time during which DNA is particularly susceptible to the...

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a) In a DNA double helix, why doesn't an A or T form two hydrogen bonds (out of the three
possible) with G or C?
b) Why is RNA structure so unstable?
c) Explain how DNA replication is bidirectional and discontinuous in nature?
d) Elaborately explain how DNA lagging strand synthesis takes place.

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In a DNA double helix, why doesn't an A or T form two hydrogen bonds (out of the three possible ) with G or C? Explain how DNA replication is bidirectional and discontinuous in nature?
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Replication involves a period of time during which DNA is particularly susceptible to the introduction of mutations. If nucleotides can be incorporated into DNA at a rate of 20 nucleotides/second and the human genome contains 3 billion nucleotides, how long will replication take? How is this time reduced so that replication can take place in a few hours?
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In the Meselson–Stahl experiment thatestablished the semiconservative nature of DNA replication,the extraction method produced short fragments of DNA. Whatsort of results might have been obtained with longer piecesof DNA?