When separating compounds by column chromatography, it is generally desirable to apply your compound mixture to the top of the column using a minimum amount of solvent. What problem often happens if you use too much solvent to "load" your compound mixture2 Why does this hannen?

Macroscale and Microscale Organic Experiments
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ISBN:9781305577190
Author:Kenneth L. Williamson, Katherine M. Masters
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Chapter9: Column Chromatography: Fluorenone, Cholesteryl Acetate, Acetylferrocene, And Plant Pigments
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Organic Chemistry, column questions

When separating compounds by column chromatography, it is generally desirable to apply
your compound mixture to the top of the column using a minimum amount of solvent.
What problem often happens if you use too much solvent to "load" your compound
mixture? Why does this happen?
Transcribed Image Text:When separating compounds by column chromatography, it is generally desirable to apply your compound mixture to the top of the column using a minimum amount of solvent. What problem often happens if you use too much solvent to "load" your compound mixture? Why does this happen?
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