Which enzyme listed below is considered both a component of the citrate cycle and a component of the electron transport system? citrate synthase, which catalyzes the reaction acetyl-CoA + oxaloacetate --> citrate Malate dehydrogenase, which catalyzes the reaction malate + NAD+ -> NADH + H+ + oxaloacetate Succinate dehydrogenase, which catalyses the reaction succinate + FAD -> fumarate + FADH2 Succinyl-CoA synthetase, which catalyses the reaction. succinyl-CoA + GDP + Pi -> succinate + GTP

Which enzyme listed below is considered both a component of the citrate cycle and a component of the electron transport system? citrate synthase, which catalyzes the reaction acetyl-CoA + oxaloacetate --> citrate Malate dehydrogenase, which catalyzes the reaction malate + NAD+ -> NADH + H+ + oxaloacetate Succinate dehydrogenase, which catalyses the reaction succinate + FAD -> fumarate + FADH2 Succinyl-CoA synthetase, which catalyses the reaction. succinyl-CoA + GDP + Pi -> succinate + GTP

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 22P: Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is...

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Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited byÂ· NIADH. Pyruvate dehydrogenase is inhibited by AÎ¤Î¡. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.
Complete oxidation of a 16-carbon fatty acid can yield 129 molecules of ATP Study Figure 19.2 and determine how many ATP molecules would be generated if a 16-carbon fatly acid were metabolized solely by the TCA cycle, in the form of S acetyl-CoA molecules.
Based on your knowledge of the structure of NAD+ and an assumption that coenzyme dissociation is the rate limiting step of the alcohol dehydrogenase mechanism, hypothesize why a N249W mutation at the coenzyme binding site would increase the rate of catalysis.
Which of the following is the third step of Citric Acid Cycle? Select one: a. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH b. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide c. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH d. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH e. Succinate is oxidized to become fumarate forming FADH2 f. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) g. Citrate is rearranged to become Isocitrate h. Malate is oxidized to become oxaloacetate forming NADH i. Fumarate is combined with water to become Malate
Determine the ATP production of glucose catabolism by glycolysis and Krebs Cycle using the following information: 1. Glycolysis: Net 2 ATP, 2 NADH + H+2. Pyruvate --> acetyl CoA: Produces 2 NADH + H+/glucose3. Krebs Cycle --> 2 FADH2 + 2 ATP + 6 NADH + H+/glucose 2.5 ATP are produced/NADH + H+ delivered electron to the electron transport system1.5 ATP are produced/FADH2 delivered electron to the electron transport system
Which of the following is the second step of Citric Acid Cycle? Select one: a. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH b. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH c. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH d. Malate is oxidized to become oxaloacetate forming NADH e. Fumarate is combined with water to become Malate f. Citrate is rearranged to become Isocitrate g. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide h. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) i. Succinate is oxidized to become fumarate forming FADH2
In order for an adipose cell to synthesize decanoic acid, it will need substrates in the form of _______ ATP, _______ NADPH from the transport of citrate into the cytoplasm and the subsequent recycling of oxaloacetate, and _______ NADPH from the pentose phosphate pathway. You can ignore the ATP used to regenerate mitochondria oxaloacetate via pyruvate carboxylase.
Which statement does NOT describe a general function of the pentose phosphate pathway? Group of answer choices The pentose phosphate pathway is used to produce NADPH for reductive biosynthesis in adipocytes. The pentose phosphate pathway allows for the entry of dietary pentose intermediates into the glycolytic pathway. The pentose phosphate pathway produces reduced molecules whose electrons may be shuttled to the mitochondria for oxidative phosphorylation. The pentose phosphate pathway allows for the conversion of hexoses into pentoses that may be used as precursors in the synthesis of nucleosides.
Which of the following events does not occur during Krebs Cycle? Citrate synthase catalyzers the transfer of an acetyl group from acetyl coenzyme A to oxaloacetate to form citrate. Isocitrate dehydrogenase converts citrate to its isomer isocitrate. A carbon dioxide is released when alpha-ketoglutarate is oxidized to succinyl coenzyme A. The energy released from the conversion of succinyl coenzyme A to succinate is used to transfer a phosphate group to ADP to form ATP. During Krebs Cycle, succinate is oxidized to fumarate which is coupled to the reduction of FAD to FADH2. During electron transport, the electrons from FADH2 are transferred to coenzyme Q. Which of the following catalyzes these reactions? NADH dehydrogenase Succinate dehydrogenase FADH2 hydrogenase NADH hydrogenase reductase
Taking into consideration glycolysis, the pyruvate dehydrogenase complex and the citric acid cycle, how many NAD+ molecules are reduced from a single molecule of dihydroxyacetone phosphate? 4 NAD+ are reduced 5 NAD+ are reduced 8 NAD+ are reduced 10 NAD+ are reduced None of the above answers are correct
Arsenate can replace inorganic phosphate in the reaction catalyzed by glyceraldehyde-3-phosphate dehydrogenase, causing glyceraldehyde-3-phosphate to be directly converted to 3-phosphoglycerate(NADH is still formed). Which of the following is absolutely true in case of arsenate poisoning -Glycolysis will stop - Glycolysis will still proceed with no net ATP gain - Glycolysis will not generate any form of energy - Glycolysis will still proceed, but with a net consumption of ATP - Glycolysis will proceed with lactate as end product
Which of the following molecules shown are the reduced products produced in the citric acid cycle whose reduction directly helped drive oxidation? Select all that apply. Ensure you are selecting the product forms of the molecule, which here means the reduced form, and are only considering redox reactions! Do not include the pyruvate processing steps -- just the citric acid cycle itself. A. GDP B. NADH C. FAD D. Acetyl-CoA E. NAD+ F. CoA G. FADH2 H. GTP I. QH2 J. Q