Biochemistry
Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 19, Problem 22P

  1. Study Figure 19.18 and decide which of the following statements is false.
  2. Pyruvate dehydrogenase is inhibited by· NIADH.
  3. Pyruvate dehydrogenase is inhibited by AΤΡ.
  4. Citrate synthase is inhibited by NADH.
  5. Succinyl-CoA activates citrate synthase.
  6. Acetyl-CoA activates pyruvate carboxylase.

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Elevated levels of acetyl-CoA will act as an effector for which of the following enzymes? more than one can be correct  Pyruvate carboxylase. Pyruvate kinase  Pyruvate dehydrogenase. Citrate synthase a-Ketoglutarate dehydrogenase.
All of the following enzymes catalyze a committed step EXCEPT: HMG-CoA reductase Fatty acyl-CoA synthetase Acetyl-CoA carboxylase I Pyruvate dehydrogenase complex All of the above enzymes catalyze a committed step   The brain can directly use all of the following chemicals as energy source EXCEPT: Acetoacetate b-hydroxybutyrate Glucose Fatty acids All of the above can directly be used by the brain as energy source
alpha-ketoglutarate dehydrogenase will do which of the following: Select one: a. Pyruvate is decarboxylated to become acetyl-CoA producing NADH and Carbon dioxide b. Succinate is oxidized to become fumarate forming FADH2 c. Succinyl-CoA becomes Succinate and forms one ATP molecule and Coenzyme A-SH d. Oxaloacetate combines with the acetyl from acetyl-CoA to produce Citric acid(citrate) e. Malate is oxidized to become oxaloacetate forming NADH f. Isocitrate and then decarboxylated and oxidized to produce alpha-ketoglutarate, Carbon dioxide and NADH g. Citrate is rearranged to become Isocitrate h. Fumarate is combined with water to become Malate i. alpha-ketoglutarate is oxidized and decarboxylated to produce Succinyl-CoA, Carbon dioxide and NADH
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