Which method - Grignard carboxylation or nitrile hydrolysis - would you use for each of the following reactions? Explain . (a) CH₂Br .CH2CO,H (c) O i CH3CCH₂CH₂CH₂I - CH3CCH₂CH₂CH₂CO₂H OH OH (b) (d) HOCH₂CH₂CH₂Br HOCH,CH,CH,CO,H Br CH3CH₂CHCH3 CH3 CH3CH₂CHCO₂H -

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter16: Chemistry Of Benzene: Electrophilic Aromatic Substitution
Section16.SE: Something Extra
Problem 62AP
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Which method - Grignard carboxylation or nitrile hydrolysis - would you use for each of
the following reactions? Explain.
(a)
CH₂Br
.CH2COzH
{c)
0
-
CH3CCH₂CH₂CH₂I
CH3CCH2CH2CH2CO2H
OH
OH
(b)
(d) HOCH2CH2CH2Br
HOCH2CH2CH2CO2H
Br
сHCHCHCH3
CH3
CH3CH₂CHCO₂H
Transcribed Image Text:Which method - Grignard carboxylation or nitrile hydrolysis - would you use for each of the following reactions? Explain. (a) CH₂Br .CH2COzH {c) 0 - CH3CCH₂CH₂CH₂I CH3CCH2CH2CH2CO2H OH OH (b) (d) HOCH2CH2CH2Br HOCH2CH2CH2CO2H Br сHCHCHCH3 CH3 CH3CH₂CHCO₂H
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