Which model (2D topology or trRosetta) is likely a better representation of the actual protein AlaE, why? COw OutsideMembraneInsideProbability1.00.80.60.40.20.000DeepTMHMM - Most Likely Topology | Type: alpha TM202040 60408060DeepTMHMM - Posterior Probabilities10080Sequence120100120140MembraneInsideOutside140

In the context of protein structure prediction, the posterior probability is generally considered a…

Answered: Which model (2D topology or trRosetta)…

Science

Biochemistry

Which model (2D topology or trRosetta) is likely a better representation of the actual protein AlaE, why?

Medical Terminology for Health Professions, Spiral bound Version (MindTap Course List)

8th Edition

ISBN:9781305634350

Author:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder

Publisher:Ann Ehrlich, Carol L. Schroeder, Laura Ehrlich, Katrina A. Schroeder

Chapter8: The Digestive System

Section: Chapter Questions

Problem 42LE: COL _________________________________________

See similar textbooks

Related questions

Q: The quantitative differences in biological activity between the two enantiomers of a compound are…

A: The atom that is connected to four different atoms or groups is called the chiral center.In general,…

Q: Please discuss the buffering capacity of an amino acid. In your answer include what is a buffer? Why…

A: Amino acids are organic compounds that serve as the building blocks of proteins. They have three…

Q: How many hydrogen bond donor groups are found in the following molecule?

A: A hydrogen bond is formed between a hydrogen bond donor and a hydrogen bond acceptor.A hydrogen atom…

Q: 2. Amino acid analysis of the a heptapeptide gave the following residues: Asp Glu Leu Lys Met Tyr…

A: The objective of the question is to determine the sequence of amino acids in a heptapeptide based on…

Q: 1. Amino Acid 1 = W + X = 1 Draw amino acid 1 at a low pH a) As the D Fisher Projection Name of…

A: The Fischer D/L configuration is set with respect to the configuration of glyceraldehyde.>Here…

Q: Is increasing the P; concentration a reasonable way to couple ATP hydrolysis and glucose…

A: When considering the phosphorylation of glucose to form glucose 6-phosphate, we have:The standard…

Q: 3. For the two compounds below, do you expect them to have identical IC50 values? Why or why not?

A: IC50 can be defined as the concentration of a substance required to inhibit a certain biological…

Q: Draw A mixed triacylglycerol that contains one saturated 8 - carbon fatty acid chain and two 6 -…

A: Triacylglycerols, or triglycerides, are fats found in living things, storing lots of energy. They're…

Q: You have an aqueous solution containing: Alaine (a mono-amino, monocarboxylic acid) Fructose (a…

A: An assay can be defined as an analytic procedure that is used in laboratory medicine, mining for…

Q: If the rate of amino acid replacement for the cytochrome c protein is 9.0E-10 replacements per amino…

A: The rate at which amino acids are changed or replaced over time in a protein sequence. the speed at…

Q: You have a peptide that has the following amino acid sequence: GPMG Draw the structure of the…

A: Peptides are short chains of amino acid residues that are linked together via a peptide bond. The…

Q: - Why Michalis plot is not used, instead double reciprocal plot is used to determine KM and Vmax?

A: The Michaelis-Menten plot and the double reciprocal (Lineweaver-Burk) plot are two common graphical…

Q: If the fermentation reactions starts out with a pH of 6.7 and the final pH is measured as 5.5 a…

A: The equation of this reaction can be written as C12H22O11(lactose) +H2O ----------->…

Q: v (mm/sec) 5.0 4.0 3.0 2.0 1.0 0.0 0.0 Estimate from the M-M plot below: Vmax, Km, Keat, and enzyme…

A: The rate (v) v/s substrate concentration ([S]) graph of enzymes that follow MM (Michaelis-Menten)…

Q: 2B. S. aureus hemolysin B attacks the RBC cell membrane by hydrolyzing the sphingomyelin headgroup:…

A: Sphingomyelin is a phospholipid which has phosphocholine as head group and sphingosine as platform…

Q: The Drug AZT is used to treat AIDS, This drug is a _____ Inhibitor/Activator of _____ a)…

A: HIV stands for human immunodeficiency virus. HIV destroys a type of white blood cells that help the…

Q: Genetics Question 3

A: The SRD5A2 gene provides instructions for making an enzyme called 5-alpha reductase 2. This enzyme…

Q: Dihybrid Cross Problem 7: Homozygous offspring of a dihybrid cross. In a dihybrid cross, AaBb x…

A: The objective of this question is to determine the fraction of offspring that will be homozygous for…

Q: Question 2 Listen The ABO gene is on a different chromosome from the +/- (Rh factor) gene. What…

A: The objective of the question is to determine the correct genetic designation for a person with O…

Q: Produces Leaves the nucleus and goes to the... 7. Transcription and Translation---DNA: A A…

A: Piece's of RNA make amino acids, which make proteins and this process occurs in the Cytoplasm. m RNA…

Q: Proteins from which compartment of the bacterial cell are likely to be found in the supernatant…

A: The objective of the question is to identify which compartments of a bacterial cell are likely to…

Q: GQ4

A: The objective of the question is to determine the number of possible gametes that an organism with 8…

Q: To better understand how the lacR works, let's start let's approximate the volume of a bacterial…

A: The bacterial cell is considered as a cylInder. The equation to find volume of cylinder is ''.

Q: Which of the following is true about a mixed type inhibition? a. None of these is true b. A…

A: The enzyme kinetics, inhibition in particular, is vital to understanding and purposefully managing…

Q: The protein catalase catalyzes the reaction 2 H,O,(aq) — 2 H₂O(1) + O₂(g) S and has a…

A: Reaction: 2H₂O₂(aq) → 2H2O(l) + O2(g)Km = 25 mMTurnover number Kcat = 4.0 × 107s–1Total enzyme…

Q: Describe how chymotrypsin is activated via a cascade mechanism in the gut. How does it incorporate a…

A: Chymotrypsin is one of the enzyme present in the digestive juices and it helps in the breakdown of…

Q: 3. You are studying an interaction between an antibody and the antigen shown below. The amine next…

A: All ionizable groups have their characteristic pKa value. pKa is the pH at which half of all the…

Q: Genetics Question 1

A: The question is asking whether genes located on different chromosomes are inherited independently of…

Q: Choose the correct structure for thiamine hydrochloride at pH 3. H3C H3C NH₂ NH₂ CI- A CI- с CH3 CH3…

A: The relationship between pH and pKa is described by the Henderson-Hasselbalch equation:pH = pKa +…

Q: Draw a phosphorylated tyrosine molecule at physiological pH. Assume that the phosphate group is…

A: Tyrosine (Tyr) is an aromatic amino acid. It plays an important role in metabolism and the…

Q: The enzyme dihydroneopterin aldolase (DHNA) is found in the metabolic pathway leading to folic acid.…

A: DHNA can catalyze two types of reactions;aldolase cleavage of DHNP to HP & GA andepimerization…

Q: Name the protein structural element shown in yellow in the figure:

A: Proteins can be defined as large biomolecules. They comprise of one or more chains of amino acids.…

Q: The enzyme that catalyzes the formation of the peptide bond is located: in the large ribosomal…

A: During translation amino acids get linked to each other via peptide bonds. The enzyme responsible…

Q: engineer the maltose binding protein (MBP) to bind 1, 3, 5 Trinitrobenzene (TNB) - a molecule that…

A: Consider the interaction of a ligand (L) with a protein (P) that leads to the formation of a…

Q: Gleevec inhibits an enzyme needed in cancer cell proliferation. It acts by increasing the enzyme's…

A: Gleevec, also known by its trade name imatinib and internationally as Glivec, is an oral medicine…

Q: A mixture of proteins contains Trypsinogen (24 kDa), fumarase (49 kDa), Transferrin (80 kDa) and…

A: Chromatography is a form of an analytical method that breaks down a chemical mixture into its…

Q: 1. In a study by Cameroni et al. (Nature, Dec. 2021), scientists analyzed the interaction between…

A: SARS-CoV-2 is an infectious virus that is responsible for the recent COVID pandemic. It is a…

Q: Determine equilibrium constants for the hydrolysis of phosphoenolpyruvate (AG" is -61.9 kJ/mol) at…

A: In order to find the value of equilibrium constant (Keq), we need to convert temperature (T) to…

Q: 2. Selective synthesis of the tetrapeptide Ala-Val-Gly-Leu a. Work backward from Structure K to fill…

A: Peptides can be synthesized chemically. For this we use various reagents like Boc (also called…

Q: 3) In his haste to create the chapter 2 homework assignment, the biochemistry professor quickly drew…

A: Amino acids are the building blocks of proteins. They have two functional groups . Amino group and…

Q: Question 4 Listen A gene known as H is epistatic to the ABO blood type genes. Based solely on this…

A: The question is asking us to determine which of the given options is possible based on the statement…

Q: In your opinion, what is the most harmful effect of widespread opioid use? Why is opioid different…

A: A class of medications known as opioids is derived from or imitates natural chemicals present in the…

Q: The bacterial gene shorty (sh) encodes for a small protein. The DNA sequence of the sh gene is shown…

A: The objective of the question is to determine the length of the Sh protein in amino acids (AA's)…

Q: Answer the following questions with regards to DNA replication: 1. In what direction does DNA…

A: DNA replication is the process of duplication of DNA by using the parent strands as template strands…

Q: Sketch the pH speciation diagram for asparagine for the range of 1 < pH < 12, annotate with the…

A: Asparagine is aliphatic, polar uncharged amino acid with carboxamide in its side chain. It is…

Q: phosphorylation/dephosphorylation Diagram the cascade that regulates glycogen metabolism. Please use…

A: Glycogen synthesis is the process of synthesizing glycogen by polymerizing glucose. It is undertaken…

Q: The Michaelis-Menten rate equation for reversible mixed inhibition is written as Vo = Vmax [S] aKm +…

A: Hence solved.Km=[S][αV0Vmax−1]Explanation:Determine the rate constant's expression, r.First, in…

Q: In the alpha helix shown below, all carbonyl groups are pointing_ amino groups are pointing…

A: The secondary structure of a protein refers to the folded configuration of the polypeptide chain.…

Q: Glycosylation is a major type of protein post-translational modification. Identify the amino acid…

A: Cavalent or generally enzymatic reactions takr place after or during translation are termed as post…

Q: An engineered ligand binds its target with 5 nM affinity at high pH. However, protonation of a…

A: An engineered ligand (L) binds to a target protein (T) to form a ligand:target complex (LT). The…

Question

Which model (2D topology or trRosetta) is likely a better representation of the actual protein AlaE, why?

Outside
Membrane
Inside
Probability
1.0
0.8
0.6
0.4
0.2
0.0
0
0
DeepTMHMM - Most Likely Topology | Type: alpha TM
20
20
40 60
40
80
60
DeepTMHMM - Posterior Probabilities
100
80
Sequence
120
100
120
140
Membrane
Inside
Outside
140

Expert Solution

This question has been solved!

Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.

SEE SOLUTION Check out a sample Q&A here

Step 1: Introduction of posterior probability

VIEW

Step 2: Brief description of posterior probability

VIEW

Solution

VIEW

Step by step

Solved in 3 steps

SEE SOLUTION Check out a sample Q&A here