49Some cells release active signaling proteins when membrane-bound precursor proteins are cleaved byproteolytic enzymes. The signaling proteins can then bind to receptors on the surface of a target cell, therebyactivating an intracellular signaling pathway and eliciting a response from the target cell.0/1This mechanism of activating receptor-binding signaling proteins has been observed in a variety oforganisms from bacteria to humans. Many of the enzymes responsible for proteolysis of membrane-boundprecursor proteins have been isolated and characterized.Which of the following questions would be most appropriate to investigate whether the proteolytic enzymesare evolutionarily conserved among species?Once the precursor proteins of different species are cleaved, do the active signaling proteins bind to thesame receptors on different target cells?If a proteolytic enzyme from one species is incubated with a precursor protein from another species, doescorrect cleavage occur?Are the proteolytic enzymes synthesized in the rough endoplasmic reticulum of all species?Are the genes encoding the proteolytic enzymes expressed in the same cell types in all species?

Proteolytic enzymes : Proteases occur in all organisms from prokaryotes to eukaryotes and to virus .…

Answered: Which of the following questions would…

Which of the following questions would be most appropriate to investigate whether the proteolytic enzymes are evolutionarily conserved among species?

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter9: Cell Communication

Section: Chapter Questions

Problem 12RQ: Histamine binds to the H1 G-protein-linked receptor to initiate the itchiness and airway...

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Concept explainers

Prokaryotic evolution

The term evolution means the gradual change or a transformation from a simple or primitive state to a complex or advanced state. Prokaryotic evolution is a concept that involves the evolution of the form and function of most primitive organisms (prokaryotes) through several stages and changes to form diverse life as a part of organic evolution.

Question

49
Some cells release active signaling proteins when membrane-bound precursor proteins are cleaved by
proteolytic enzymes. The signaling proteins can then bind to receptors on the surface of a target cell, thereby
activating an intracellular signaling pathway and eliciting a response from the target cell.
0/1
This mechanism of activating receptor-binding signaling proteins has been observed in a variety of
organisms from bacteria to humans. Many of the enzymes responsible for proteolysis of membrane-bound
precursor proteins have been isolated and characterized.
Which of the following questions would be most appropriate to investigate whether the proteolytic enzymes
are evolutionarily conserved among species?
Once the precursor proteins of different species are cleaved, do the active signaling proteins bind to the
same receptors on different target cells?
If a proteolytic enzyme from one species is incubated with a precursor protein from another species, does
correct cleavage occur?
Are the proteolytic enzymes synthesized in the rough endoplasmic reticulum of all species?
Are the genes encoding the proteolytic enzymes expressed in the same cell types in all species?

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