Which of the following reactions does NADH act as coenzyme? A. "glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate" B. pyruvate to acetyl-CoA C. isocitrate to a-ketoglutarate D. pyruvate to lactate
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CHOOSE THE CORRECT LETTER
Which of the following reactions does NADH act as coenzyme?
A. "glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate"
B. pyruvate to acetyl-CoA
C. isocitrate to a-ketoglutarate
D. pyruvate to lactate
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- Which of the following enzymes possesses a catalytic mechanism extremely similar to that of the Pyruvate Dehydrogenase Complex? A. the isocitrate dehydrogenase B. the succinate dehydrogenase C. the alpha-ketoglutarate dehydrogenase D. the malate dehydrogenaseIdentify the Krebs cycle enzyme that consumes a six-carbon substrate molecule, producing a six-carbon product molecule, but neither consumes nor produces NADH? A. a-ketoglutarate dehydrogenase B. isocitrate dehydrogenase C. succinyl CoA synthetase D. malate dehydrogenase E. aconitaseCertain tissues, such as the heart muscle, can use lactate as an energy substrate. How much ATP is formed during the oxidation of one lactate molecule to CO2 and H2O? write the reactions of the complete oxidation of lactate.
- The initial step of the citric acid cycle is a. Conversion of pyruvate to acetyl-CoA b. Formation of ? -ketoglutarate catalysed by isocitrate dehydrogenase c. Condensation of acetyl-CoA with oxaloacetate d. Conversion of citrate to isocitrateNAD is reduced in which Citric Acid cycle reaction? (a) Isocitrate to oxaloacetate (b) alpha-ketoglutarate to Succinyl CoA (c) Malate to oxaloacetate (d) Succinate to fumarate (e) Oxaloacetate to CitrateWhich of the following citric acid cycle enzymes catalyzes substrate-level phosphorylation? A) isocitrate dehydrogenase B) α-ketoglutarate dehydrogenase C) succinyl CoA synthetase D) succinate dehydrogenase E) malate dehydrogenase
- Which of the following is the chemical end product of fatty-acids metabolized in the beta-oxidation pathway? Select one: a. Beta-carotine b. Free-radicals c. Lactic acid d. Acetyl-CoA e. PyruvateExplain the advantage to the cell of each of the following regulatory actions: a. The pyruvate dehydrogenase complex (PDC) is inhibited by ATP.b. Isocitrate dehydrogenase is stimulated by ADP.c. Pyruvate carboxylase is stimulated by acetyl-CoA.d. Citrate synthase is inhibited by NADH.e. PDC is inhibited by fatty acidsWhich of the following is NOT a component of the pyruvate dehydrogenase complex? a. dihydrolipoyl dehydrogenase b. dihydrolipoyl transacetylase c. pyruvate dehydrogenase d. dihydrolipoyl catalase
- During strenuous exercise, the NADH formed in the glyceraldehyde 3-phosphate dehydrogenase reaction in skeletal muscle must be reoxidized to NAD+ if glycolysis is to continue. The most important reaction involved in the reoxidation of NADH is: a. dihydroxyacetone phosphate → glycerol 3-phosphate b. glucose 6-phosphate → fructose 6-phosphate c. isocitrate → α-ketoglutarate d. oxaloacetate → malate e. pyruvate → lactateWhich of the following coenzymes does not get restored to it's original form within the PDH complex once pyruvate gets converted to acetyl CoA a. NAD+ b. TPP c. Lipolic Acid d. FADSelect the correct statement for pyruvate dehydrogenase (a) Catalyses oxidative decarboxylation (b) Requires coenzymes like NAD+ (c) Require cofactor Mg++ a.Only b b.Only b and c c.Only c d.All a,b and c