Which of the following regulatory mechanisms will specifically inhibit pyrimidine synthesis (and not also purine synthesis)? (A) allosteric regulation of aspartate transcarbamoylase by CTP (B) allosteric regulation of aspartate transcarbamoylase by ATP (C) synergistic inhibition of PRPP synthetase by AMP/GMP/IMP (D) synergistic inhibition of PRPP amidotransferase by AMP/GMP/IMP (E) feedback inhibition of ribonucleotide reductase by dATP

Which of the following regulatory mechanisms will specifically inhibit pyrimidine synthesis (and not also purine synthesis)? (A) allosteric regulation of aspartate transcarbamoylase by CTP (B) allosteric regulation of aspartate transcarbamoylase by ATP (C) synergistic inhibition of PRPP synthetase by AMP/GMP/IMP (D) synergistic inhibition of PRPP amidotransferase by AMP/GMP/IMP (E) feedback inhibition of ribonucleotide reductase by dATP

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter26: Synthesis And Degradation Of Nucleotides

Section: Chapter Questions

Problem 14P: The Energy Cost of dTTP Synthesis (Integrates with Chapter 20.) Starting from HCO3, glutamine,...

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