Which of the following statements about mendelian or complex diseases true?. A Genome- wide association studies rely on polymorphic markers that are linkage disequalibrium with alleles that contribute to the traits of interest. B. Genetic methods for studying Mendelian phenotype such as crossing is not useful for mapping quantitive trait loci. C. Mapping of quantitative trait loci does relies on genetic variations that directly contribute to the trait of interest.

Which of the following statements about mendelian or complex diseases true?. A Genome- wide association studies rely on polymorphic markers that are linkage disequalibrium with alleles that contribute to the traits of interest. B. Genetic methods for studying Mendelian phenotype such as crossing is not useful for mapping quantitive trait loci. C. Mapping of quantitative trait loci does relies on genetic variations that directly contribute to the trait of interest.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter18: Genetics Of Behavior

Section: Chapter Questions

Problem 14QP: A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known...

See similar textbooks

Similar questions

If, within specific regional populations over two thousand years ago, sickle-cell anemia killed those individuals born with it before they could reproduce to pass it on to offspring, how did it persist in these populations? Group of answer choices A-Because of late-onset of the disease. B-Because it is cause by a virus and it spreads faster than people died. C-Because of the basic principles of mendelian inheritance that result in some heterozygote "carrier" combinations. D-Because malaria made it possible to survive sickle cell anemia since the parasite would carry oxygen on the blood cells with the mutated hemoglobin. E-It does not persist. Natural selection removes the allele because people die from both malaria and sickle-cell anemia.
Consider the case of a hypothetical genetic disease called WhySciEleven (WSE), an inherited disease that results to the inability to complete production of an amino acid “moduleactivity” that results in brain damage if untreated. WSE is due to a recessive allele. Given one WSE occurrence per 10,000 births. Which term in the Hardy-Weinberg equation corresponds to the frequency of individuals who have no alleles for the disease WSE? a. p b. 2pq c. p2 d. q2
The following table shows the number of dogs for certain tail lengths in a population of dogs. Tail Length Number of Dogs very short (less than 1 inch) 2 short (1–5 inches) 5 medium (5–10 inches) 15 long (10–15 inches) 5 very long (15–25 inches) 2 Based on this data, what type of trait is tail length in dogs? (a) Mendelian (b) codominant (c) (d) polygenic
Identify each of the following as an example of allele, genotype, and/or phenotype frequency: A. Approximately 1 in 2500 people of Northern European descent is born with cystic fibrosis. B. The percentage of carriers of the sickle cell allele in West Africa is approximately 13%. C. The number of new mutations for achondroplasia, a genetic disorder, is approximately 5 × 10–5.
Cystic fibrosis (CF) is a recessive autosomal disorder. In certain populations of Northern European descent, the number of people born with this disorder is about 1 in 2500. Assuming Hardy- Weinberg equilibrium for this trait: A. What are the frequencies for the normal and CF alleles? B. What are the genotype frequencies of homozygous normal, heterozygous, and homozygous affected individuals? C. Assuming random mating, what is the probability that two phenotypically unaffected heterozygous carriers will choose each other as mates?
What is the Chi-squared Goodness of Fit test used to test? a. If the disease is due to environmental or genetic factors. b. The name of the disease gene. c. Whether the disease follows a AR or AD mode of inheritance at the disease gene. d. If the p-value is greater than 0.05. e. If the observed data is consistent with the specified mode of inheritance at a given disease gene.
What is a quantitative trait locus (QTL)? a. A portion of the genome that is a particular quantitative length b. A portion of the genome in which polymorphic markers correlate with a phenotype c. A region of the genome where qualitative traits associate with discrete phenotypes d. A region of the genome that does not follow Mendelian inheritance patterns
In Huntington’s disease, the wild-type allele, h, is recessive to the disease allele, H. The persistence of an autosomal dominant allele that is fatal in 100% of cases is best explained by which of the following? A) The dominant allele only has moderate negative effects during adolescence and young adulthood. B) The wild-type h allele continues to spontaneously mutate into the dominant H allele. C) The persistence of any given allele in nature is determined almost wholly by chance. D) The disease has no effects until the individual has reached an age far past the normal age for reproduction.
Please use the following table to compare qualitative (Mendelian) traits and quantitative traits (complex traits) - choose from the following.
Consider the following scenario: A man without freckles (freckles are a dominant trait, determined by the dominant allele “F”) is a carrier of cystic fibrosis (recall that CF is a recessive trait, determined by the recessive allele "a"), mates with a woman whose genotype is heterozygous for freckles and is also a carrier of CF. Assume the two genes in question are in different chromosomes and, therefore, assort independently. Complete the following Punnett square to generate the offspring probabilities from this couple, by entering the genotypes of the parents, the gametes, and the offspring for the two traits described above. (4) Father’s genotype ffAa Mother’s genotypeFfAa ● Sperm: fA ● Sperm: fa ● Sperm: fA ● Sperm: fa ● Egg: FA ● Egg: fA ● Egg: Fa ● Egg: fa What is the probability for this couple to have a child with freckles? What is the…
A) what are the genotypes for EB27 and EB67? B) what is the relationship between the three alleles (B,br, y)? Show evidence using the pedigree
In 1927, the ophthalmologist George Waaler tested9049 schoolboys in Oslo, Norway, for red-green colorblindness and found 8324 of them to be normal and725 to be color blind. He also tested 9072 schoolgirlsand found 9032 that had normal color vision while40 were color blind.a. Assuming that the same sex-linked recessive allelec causes all forms of red-green color blindness,calculate the allele frequencies of c and C (the allelefor normal vision) from the data for the schoolboys.(Hint: Refer to your answer to Problem 12a.)b. Does Waaler’s sample demonstrate Hardy-Weinbergequilibrium for alleles of this gene? Explain youranswer by describing observations that are eitherconsistent or inconsistent with this hypothesis.On closer analysis of these schoolchildren, Waalerfound that there was actually more than one c allelecausing color blindness in his sample: one kind forthe prot type (cp) and one for the deuter type (cd).(Protanopia and deuteranopia are slightly differentforms of red-green…