Which of the following statements are TRUE? Multiple answers: You can select more than one option Water is unusual in that its solid form is less dense than its liquid form. A Glu residue in a receptor protein is altered to Ala in a site-directed mutagenesis experiment. Binding of the ligand to the mutant receptor decreases 100-fold. From this we could conclude that the ligand has a positive charge and forms an ion pair with negatively charged Glu on the receptor. O B In three separate site-directed mutagenesis experiments - scientists altered a Lys residue in corn PEP Carboxylase to an Asn - Glu - or Arg. The substitution that would have the least effect on enzymatic activity is that of Arg. Myoglobin is a protein that contains mostly alpha helices and no beta sheets. Under certain laboratory conditions - myoglobin can be induced to form amyloid (beta sheet like) fibers. This suggests that any polypeptide-even one whose native conformation is all alpha helical-can assume beta conformation if conditions permit. The Grelag goose lives year-round in the Indian plains. Its close relative the Bar-headed goose lives in the Tibetan Himalayas. If transfer of oxygen to tissues is the primary function of hemoglobin then one would expect the Bar-headed goose hemoglobin to have a lower P50 value corresponding to higher oxygen affinity in comparison to the plains-dwelling Grelag goose hemoglobin.
Which of the following statements are TRUE? Multiple answers: You can select more than one option Water is unusual in that its solid form is less dense than its liquid form. A Glu residue in a receptor protein is altered to Ala in a site-directed mutagenesis experiment. Binding of the ligand to the mutant receptor decreases 100-fold. From this we could conclude that the ligand has a positive charge and forms an ion pair with negatively charged Glu on the receptor. O B In three separate site-directed mutagenesis experiments - scientists altered a Lys residue in corn PEP Carboxylase to an Asn - Glu - or Arg. The substitution that would have the least effect on enzymatic activity is that of Arg. Myoglobin is a protein that contains mostly alpha helices and no beta sheets. Under certain laboratory conditions - myoglobin can be induced to form amyloid (beta sheet like) fibers. This suggests that any polypeptide-even one whose native conformation is all alpha helical-can assume beta conformation if conditions permit. The Grelag goose lives year-round in the Indian plains. Its close relative the Bar-headed goose lives in the Tibetan Himalayas. If transfer of oxygen to tissues is the primary function of hemoglobin then one would expect the Bar-headed goose hemoglobin to have a lower P50 value corresponding to higher oxygen affinity in comparison to the plains-dwelling Grelag goose hemoglobin.
Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter23: Enzymes
Section: Chapter Questions
Problem 23.36P
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