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- Which of the following concerning glucagon is TRUE? a. It is a hormonal protein that uptakes glucose and amino acids from blood. b. Its activity is up-regulated when blood glucose increases. c. It is a hormonal protein that up-regulates glycogenolysis. d. It decreases gluconeogenesis.Islet cells in the pancreas are actively synthesizing and secreting insulin into the bloodstream. A scientist purifies different membranous fractions of these islet cells. In which fraction would she find insulin or its intermediates?Which of the following statements about insulin is not true? a. The insulin receptor has tyrosine kinase activity. b. Insulin increases fat synthesis in adipose cells. c. Insulin increases glycogen synthesis d. Insulin increases gluconeogenesis reactions.
- Insulin stimulates which of the following pathways? a. Gluconeogenesis b. Triacylglycerol synthesis and storage c. Lipolysis and fatty acid mobilization d. Glycogen breakdown. Which of the following pathways is not stimulated by epinephrine? a. Glycogen degradation b. Mobilization of fatty acids from adipose tissue c. Glycogen synthesis d. Glycolysis in muscleWhich of the following are metabolic fight or flight responses? a. decreased glycolysis in the muscles b. decreased adrenalin : insulin c. increased gluconeogenesis in the liver d. increased glycogen synthesis in the liver e. increased insulin : glucagon
- It is noticed that when a strain of mice exercises, their blood glucose drops to very low levels. Which of the following can explain this situation? a) These mice do not make enough insulin b) these mice lack insulin receptors on their cells c)these mice lack glucagon d) these mice cannot synthesize glycogen from glucoseWhy would a cause of hyperinsulinism be hypoglycemia? Don’t lower levels of blood glucose inhibit of insulin rather than produce large amounts of it to result in hyperinsulinism?As a result of complete fasting for 3 days, a significant change in metabolism occurs. How will the level of fatty acids in the blood change? What hormone causes these changes? Justify your answer schematically.
- Glucagon: a. Increases glucose transport to skeletal muscle cells b. Increases glycogen synthesis in liver cells c. Inhibits gluconeogenesis in liver d. Increases cellular cAMP level e. Inhibits glucose synthesis in hypoglycemiaThe chemical bisphenol-A (BPA) is used to make plastic bottles and to line cans. Evidence from animal experiments and epidemiological studies indicates that the risk of obesity rises with increased BPA intake. How might the endocrine-disrupting effects of such a chemical influence body weight?Which of the following statements about glucagon is true? a. Glucagon causes glycogen to break down to form glucose. b. Glucagon secretion is highest following a heavy meal. c. Glucagon promotes the uptake of glucose by liver and muscle cells. d. Glucagon works with cortisol to lower blood glucose levels.
