Which type(s) of chromosome structure variation could result in the chromosome being a different overall length compared to its normal-structure homolog? (Select all that apply.) deletion O duplication O inversion translocation
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- In an electrophoretic gel across which is applied a powerful electrical alternating pulsed field, the DNA of thehaploid fungus Neurospora crassa (n = 7) moves slowlybut eventually forms seven bands, which represent DNAfractions that are of different sizes and hence havemoved at different speeds. These bands are presumed tobe the seven chromosomes. How would you show whichband corresponds to which chromosome?To which chromosome and which band does the sequence localise? Write the location in the standard format: e.g. 8q21.3, not Chr 8 (q21.3). *clone number in this case is 196 which is shown in the images*Karyogram and Identification of Chromosomal Aberrations List down five human chromosomal aberrations. Give the corresponding karyotype for each type then briefly describe the traits of affected individuals.
- A blood stain from a crime scene and blood samples from four suspects were analyzed by PCR using fluorescent primers associated with three STR loci: D3S1358, vWA, and FGA. The resulting electrophoretograms are shown below. The numbers beneath each peak identify the allele (upper box) and the height of the peak in relative fluorescence units (lower box). Solve, (a) Since everyone has two copies of each chromosome and therefore, two alleles of each gene, what accounts for the appearance ofonly one allele at some loci? (b) Which suspect is a possible source of the blood? (c) Could the suspect be identifi ed using just one of the three STR loci? (d) What can you conclude about the amount of DNA obtained from Suspect 1 compared to Suspect 4?If you are comparing the two telomeres in each entryin the following list, in which cases would you expectthe two telomeres always to have exactly the samenumber of TTAGGG repeats?a. One telomere at one end of a chromosome, one telomere at one end of a nonhomologous chromosome.b. One telomere at one end of a chromosome, onetelomere at the corresponding end of the homologous chromosome.Here are the results of the testcross:Green-eyes, wild-type wings 245Green-eyes, miniature wings 232Wild-type eyes, wild-type wings 250Wild-type eyes, miniature wings 2386.) In your opinion, is the grn gene on the same chromosome as the min gene? How do you know?Next, you set up another experiment to determine if grn is on chromosome #1. The only appropriate fliesthat you have handy are double-mutants for the black-body mutation (blk) and curved wings mutation(crv), but this should work just fine. First, you conduct a series of crosses to generate a strain of triple-mutant flies (grn blk crv). Then, you cross those with wild-type flies to generate triple hybrids.7.) What are the genotype(s) and phenotype(s) of the progeny of this cross?Next, you set up a testcross to reveal any linkage between the three genes.8.) What are the genotypes and phenotypes of this testcross?
- If you are comparing the two telomeres in each entryin the following list, in which cases would you expectthe two telomeres always to have exactly the samenumber of TTAGGG repeats?a. One telomere at one end of a chromosome, one telomere at one end of a nonhomologous chromosome.b. One telomere at one end of a chromosome, onetelomere at the corresponding end of the homologous chromosome.c. One telomere at one end of a chromosome, theother telomere at the other end of the samechromosome.d. One telomere at one end of a chromatid, the othertelomere at the corresponding position in the sisterchromatid.When stained with Giemsa (G-Banding staining), the centromere will be stained: Question 28 options: more robustly (dark band) less robustly (light band)A heterozygous reciprocal translocation involving 2 non-homologous chromosomes resulted to a new sequence ABCDXYZ and TUVWEFG. Illustrate the chromosomes before and after translocation and the pachytene configuration of the chromosome after translocation.
- . Genomes A, B, and C all have basic chromosomenumbers (x) of nine. These genomes were derivedoriginally from plant species that had diverged from each other sufficiently far back in the evolutionarypast that the chromosomes from one genome can nolonger pair with the chromosomes from any other genome. For plants with the following kinds of euploidchromosome complements, (i) state the number ofchromosomes in the organism; (ii) provide terms thatdescribe the individual’s genetic makeup as accurately as possible; (iii) state whether or not it is likelythat this plant will be fertile, and if so, give the number of chromosomes (n) in the gametes.a. AABBCb. BBBBc. CCCd. BBCCe. ABCf. AABBCCSuppose the banding pattern variation for chromosome 9 in sharks arose in the given order. The ancestral chromosome is numbered 7654321. Identify which chromosomal modifications are responsible for the banding pattern changes observed in each of the novel chromosomes. Thank you for your assistance and to show my appreciation an immediate like is guaranteed if answered correctly.Inversions are said to “suppress crossing over.” Is this terminologytechnically correct? If not, restate the descriptionaccurately.